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Hisense Unveils New Tagline “Hisense, More Than a Brand” Marking Major Branding Initiative

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QINGDAO, China, July 5, 2024 /PRNewswire/ — Global home appliance and consumer electronics leader Hisense recently revealed its new brand tagline, “Hisense, More Than a Brand,” marking a significant new branding initiative during the UEFA EURO 2024™ matches.

Recently, the new tagline “Hisense, More Than a Brand” appeared together with the brands of Hisense, ASKO, Gorenje on the pitch. This latest brand enhancement underscores Hisense’s unwavering commitment to establishing a strong global presence, reflected in the company’s strategic sports marketing investments, and continued long-term football relationship as official partner of UEFA EURO 2024™ in particular.

Hisense new tagline at UEFA EURO 2024™
Hisense new tagline at UEFA EURO 2024™

In fact, Hisense’s messaging has evolved along with their global ambitions and football sponsorships, progressing from “Hisense TV #2 GLOBALLY Hisense TV #1 IN CHINA” at the FIFA World Cup 2022™ to “Never Settle for No. 2 Globally” at UEFA EURO 2024™ with a comprehensive layout of display technology and smart home appliances this year. The company’s strategy of long-term sports sponsorship has boosted global brand awareness to 54% according to Ipsos 2023. According to Omdia, Hisense Q1 2024 global TV shipment volume share was 13.6% with a global shipment revenue share of 12.1%. Hisense is now currently ranked No. 2 globally for TV shipments and No. 1 in 100″ TVs in both 2023 and Q1, 2024.

Applying a multi-brand strategy, Hisense Group has several other brands, including Toshiba TV, Kelon, Gorenje, ASKO, VIDAA, SANDEN, Regza, MORA, etc. Through years of internal cultivation and external acquisitions, the company has entered the stage of multi-brand global operation and development, forming a complete and rich brand matrix. This has resulted in a complete and diverse brand matrix that allows for different brand strategies in various business fields and market segments, catering to the preferences and needs of different consumers.

In striving to become a world-class enterprise with a globally recognized reputation, Hisense is undergoing rapid international expansion with effectively implementing strategies of independent and high-end brand globalization over the years. 

With a robust global network encompassing 34 industrial parks, 26 R&D centers, and 64 overseas offices, Hisense boasts a workforce of 110,000 employees, with some 24,000 comprising international staff. This extensive network fuels the development of cutting-edge products, optimized manufacturing with a global supply chain and tailored marketing strategies for specific regions. Understanding technological innovation is the key to future success, Hisense will continue to invest in R&D in developing cutting-edge, innovative products dedicated to improving people’s lives. In prioritizing user needs, in 2023 the company implemented a “user-centered, scenario-driven strategy” to gain a deeper understanding of consumer needs. This focus directly translates into their latest 2024 brand upgrade, which emphasizes “user-centric technology” and “ultimate quality”.

Hisense’s commitment extends beyond superior picture quality and performance. Through recognizing the importance of catering to diverse consumer needs, prioritizing local preferences with effective supply chain adaptations and building strong communication bridges under the leadership of “local for local”, Hisense has transformed into a leading international brand, embedding innovative science and technology into the lifestyles of consumers worldwide.

About Hisense

Hisense is a leading global home appliance and consumer electronics brand and official partner of the UEFA EURO 2024™. According to Omdia, Hisense ranked No. 2 globally for TV shipments and No. 1 in 100″ TVs in both 2023 and Q1 2024. The company has expanded quickly to operate in more than 160 countries and specializes in multi-media goods, home appliances, and intelligent IT information.

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FAIR PLAY MENARINI INTERNATIONAL AWARD, A MAGICAL NIGHT AT FIESOLE FOR THE GRAND FINALE

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FLORENCE, Italy, July 5, 2024 /PRNewswire/ — A finale to remember: the sporting legends delighted the packed terraces of the Roman Theatre in Fiesole, bringing the curtain down on the 28th Fair Play Menarini International Award. Yesterday, the event dedicated to the values of ethics, loyalty, and respect, celebrated the winners of the 2024 edition at the awards ceremony, shining examples of fair play and sportsmanship in competition and in life.

28th Fair Play Menarini Award
28th Fair Play Menarini Award

Icons from the international stage were greeted by the applause of the spectators at the Roman Theatre. Starting with Samuel Eto‘o, representing the very best of the world of football and the time-honoured glory of Cameroon and Fabio Cannavaro, captain of Italy’s winning 2006 World Cup team. Alongside them, two legendary players for the Italian side: Ciro Ferrara, runner-up in the 2000 European Cup, and Giuseppe Dossena, hero of Italy’s 1982 World Cup campaign in Spain. A line-up brought to a close by head coach, Cesare Prandelli, who led the Italian team to second place in the European Cup in 2012.

Among the outstanding athletes who graced the Fair Play Menarini red carpet were speed skating queen, Francesca Lollobrigida, triumphant at the 2018 European Championships, and sprinter, Ambra Sabatini, Italian flag bearer at the Paris Paralympics. Basketball was also proudly represented by Marco Belinelli, outstanding NBA player, while taking centre stage for volleyball was Gian Paolo Montali, former head coach of the Men’s National volleyball team, twice European champions. Not forgetting, Roberto Rigali, silver medallist in Budapest in 2023 in the 4×100 relay, the rally and F1 icon, Cesare Fiorio, and multiple world heavyweight boxing champion, Clemente Russo. Lastly, sports journalism was honoured by Federico Buffa, the voice and face of great sporting events.

The Fair Play Menarini Ambassadors, preceding them in the Hall of Fame, were there to hand over the awards. Among them the “Divina” Federica Pellegrini, winner of the 2022 edition and star guest of the event, together with hosts, Rachele Sangiuliano and Omar Schillaci, for the first edition of the Awards in partnership with Sky TG24. A recording of the awards ceremony will be broadcast on Sportitalia.

It was an unforgettable edition, honouring a whole host of sporting legends – stated Antonello Biscini, Valeria Speroni Cardi, and Ennio Troiano, Members of the Board of the Fair Play Menarini Foundation – What that makes us most proud is the overwhelming participation of the public and the enthusiasm of the younger generations, which just go to show how the values of fair play are an integral part of our society. We will take away with us these emotions and look forward to unveiling the surprises at next year’s Award“.

Here is the list of the winners of the 28th Fair Play Menarini International Award:
SAMUEL ETO‘O
MARCO BELINELLI
FEDERICO BUFFA
FABIO CANNAVARO
GIUSEPPE DOSSENA
CIRO FERRARA
CESARE FIORIO
FRANCESCA LOLLOBRIGIDA
GIAN PAOLO MONTALI
CESARE PRANDELLI
ROBERTO RIGALI
CLEMENTE RUSSO
AMBRA SABATINI

28th Fair Play Menarini Award: awardee Samuel Eto’o
28th Fair Play Menarini Award: awardee Samuel Eto’o
28th Fair Play Menarini Award: awardees Fabio Cannavaro and Ciro Ferrara
28th Fair Play Menarini Award: awardees Fabio Cannavaro and Ciro Ferrara

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XPOVIO® (selinexor) Approved for New Indication in DLBCL in China, Bringing a New Treatment Option to Patients in the Country

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– Following its initial approval for the treatment of relapsed/refractory multiple myeloma (R/R MM), XPOVIO® has now received approval as a monotherapy for the treatment of adult patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) marking the second approved indication of XPOVIO® in China.
– Results from the registrational SEARCH study in China showed that the overall response rate (ORR) among the 60 Chinese patients treated with XPOVIO® met the study’s prespecified primary endpoint.
– XPOVIO® is an oral drug with a novel mechanism of action. Antengene is currently developing multiple combination regimens of XPOVIO® for the treatment of various indications including myelofibrosis (MF), T-cell non-Hodgkin’s lymphoma (T-NHL), and endometrial cancer.
– XPOVIO® has been approved for health insurance coverage in the mainland of China, Australia, Singapore and South Korea. Furthermore, Antengene has submitted new drug applications (NDAs) for XPOVIO® in other ASEAN markets including Thailand, Malaysia and Indonesia. Approvals in these markets are anticipated in the second half of 2024.

SHANGHAI and HONG KONG, July 5, 2024 /PRNewswire/ — Antengene Corporation Limited (“Antengene”, SEHK: 6996.HK), a leading innovative, commercial-stage global biopharmaceutical company dedicated to discovering, developing and commercializing first-in-class and/or best-in-class medicines for cancer, today announced that the China National Medical Products Administration (NMPA) has approved a new indication of XPOVIO® (selinexor) as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).

A Novel Therapy Bringing Long-awaited Clinical Breakthrough to the Treatment of R/R DLBCL

DLBCL is one of the most common subtypes of non-Hodgkin lymphoma (NHL) in adults and is highly heterogeneous malignancy in both clinical manifestations and prognosis. The current standard treatment, immunotherapy, offers patients with DLBCL a five-year progression-free survival rate of 60%-65% and curative outcomes for 40%-50% of treated patients. However, 10%-15% of DLBCL patients do not respond to standard first-line treatment, and 20%-25% experience relapses after achieving initial responses, leading to a poor prognosis and enormous unmet clinical needs.

The Clinically Validated Efficacy and Convenience of Oral Administration of Selinexor Offer Benefits to a Broad Spectrum of Patients

The approval for the new indication was supported by data from the registrational SEARCH study in China. Results from the study, which enrolled a total of 60 Chinese patients with DLBCL, showed that patients treated in the trial achieved a central radiological review assessed overall response rate (ORR) meeting the pre-specified primary endpoint. The SEARCH study demonstrated clear efficacy of orally-administered selinexor monotherapy in Chinese patients, exhibiting significant response rates, durable responses, long survival. 

Prof. Jun Zhu, principal investigator of the SEARCH study from Peking University affiliated Beijing Cancer Hospital, said, “DLBCL is the most common subtype of NHL in adults and accounts for 40% of all NHL cases in China. The incidence of NHL has been steadily rising year over year, while patients with third- and later-lines relapsed or refractory disease lack effective and convenient therapies. As a nuclear export protein inhibitor with a novel mechanism of action (MOA), selinexor offers patients a new treatment option that is efficacious and easy to use, with oral availability that can reduce hospitalization and financial burden on patients by allowing them to receive treatment at home. Overall, the approval for this new indication of selinexor is indeed a great news for Chinese patients with R/R DLBCL.”

Approved in 40+ Markets Globally with Expanding Insurance Coverage Across APAC

With a novel mechanism of action, XPOVIO® is the world’s first approved orally-available, selective XPO1 inhibitor. XPOVIO® has a global commercial presence with approvals in over 40 countries and regions. To date, XPOVIO® has already been included for health insurance coverage in the mainland of China, Australia, Singapore and South Korea. Antengene has also submitted the NDAs in additional ASEAN markets, including Thailand, Malaysia and Indonesia, where approvals are expected in the H2 of 2024.

About XPOVIO® (selinexor)

XPOVIO® is the world’s first approved orally-available, selective inhibitor of the nuclear export protein XPO1. It offers a novel mechanism of action, synergistic effects in combination regimens, fast onset of action, and durable responses.

By blocking the nuclear export protein XPO1, XPOVIO® can promote the intranuclear accumulation and activation of tumor suppressor proteins and growth regulating proteins, and down-regulate the levels of multiple oncogenic proteins. XPOVIO® delivers its antitumor effects through three mechanistic pathways: 1) exerting antitumor effects by inducing the intranuclear accumulation of tumor suppressor proteins; 2) reducing the level of oncogenic proteins in the cytoplasm by inducing the intranuclear accumulation of oncogenic mRNAs; 3) restoring hormone sensitivity by activating the glucocorticoid receptors (GR) pathway. To utilize its unique mechanism of actions, XPOVIO® is being evaluated for use in multiple combination regimens in a range of indications. At present, Antengene is conducting multiple clinical studies of XPOVIO® in the mainland of China for the treatment of relapsed/refractory hematologic malignancies and solid tumors (3 of these studies are being jointly conducted by Antengene and Karyopharm Therapeutics Inc. [Nasdaq:KPTI]).

About Antengene

Antengene Corporation Limited (“Antengene”, SEHK: 6996.HK) is a leading commercial-stage R&D-driven global biopharmaceutical company focused on the discovery, development, manufacturing and commercialization of innovative first-in-class/best-in-class therapeutics for the treatment of hematologic malignancies and solid tumors, in realizing its vision of “Treating Patients Beyond Borders”.

Since 2017, Antengene has built a pipeline of 9 oncology assets at various stages going from clinical to commercial, including 6 with global rights, and 3 with rights for the APAC region. To date, Antengene has obtained 29 investigational new drug (IND) approvals in the U.S. and Asia, and submitted 10 new drug applications (NDAs) in multiple Asia Pacific markets, with the NDA for XPOVIO® (selinexor) already approved in Mainland of China, Taiwan China, Hong Kong China, Macau China, South Korea, Singapore and Australia.

Forward-looking statements

The forward-looking statements made in this article relate only to the events or information as of the date on which the statements are made in this article. Except as required by law, we undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this article completely and with the understanding that our actual future results or performance may be materially different from what we expect. In this article, statements of, or references to, our intentions or those of any of our Directors or our Company are made as of the date of this article. Any of these intentions may alter in light of future development. For a further discussion of these and other factors that could cause future results to differ materially from any forward-looking statement, please see the other risks and uncertainties described in the Company’s Annual Report for the year ended December 31, 2023, and the documents subsequently submitted to the Hong Kong Stock Exchange.

For more information, please contact:

Investor Contacts: 
Donald Lung
E-mail: Donald.Lung@antengene.com 
Mobile: +86 18420672158

PR Contacts:
Peter Qian
E-mail: Peter.Qian@antengene.com 
Mobile: +86 13062747000

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Op-ed: Avoid those vacation photo-ops to actually enjoy the moment

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Why 36% of Americans say they're willing to go into debt to pay for vacation

Two winters ago, we vacationed to a hot-spot resort in the Caribbean with our family. Around the perimeter of its casino concourse, a variety of attractions buzzed for our consumption.

We found an art installation to climb on, faux floral arches to position ourselves around and giant milkshakes topped with full desserts in sugar-rimmed glasses to sip from — well, not before the photos.

Photos came first.

To be honest, it felt less like a vacation and more like a visit to one of those immersive exhibits where everything’s a photo-op and everyone you know has taken the same exact photos there. This is because they have taken the same exact photos there, and doubtless, geotagged their location.

More from CNBC’s Advisor Council

Social media has transformed the reason we take photos on vacation. According to a survey conducted by Forbes Advisor, 82% of Gen Zers and 57% of millennials visit certain destinations because they saw them on social media. Many people post their travels in real time, engaging in a perpetual game of capture and share. According to the same survey, 74% of respondents feel some kind of pressure to imitate the travel content they consume online.

Without question, we fell into that camp on our vacation. It was performative, exhausting, and above all, absurdly expensive.

Don’t get us wrong — we love social media for connecting with friends, drawing inspiration from others, and yes, even drooling a bit over beautiful destinations. But its hazard lies in clouding your better judgment when making financial decisions that might not be worth it in real life.

This summer, a little more than half of Americans are planning to take a vacation, according to a Bankrate survey. Out of those travelers, 36% are prepared to take on debt to pay for it. Costs continue to rise across the board for flights, accommodations, even dining, and consumer buying is keeping pace. In the process, many travelers are losing sight of their long-term goals to capture something that feels important in a moment but isn’t at all.

‘Pics or it didn’t happen’ comes at a cost

Morsa Images | Digitalvision | Getty Images

You lose the plot — and your money — when what’s supposed to be for you becomes about showcasing it for everyone else. It’s a classic case of “pics or it didn’t happen.” You can end up spending more time focused on the wrong elements of your vacation, like positioning yourself for the perfect sunset photo-op but then not watching the actual sunset, or filming half of a concert with the camera flipped around on you.

We’ve all done this; it’s no one person’s fault. But is snapping those pics worth paying inflated prices? Going into credit card debt? Stretching your annual vacation budget to accommodate the resort everyone claims to love so much?

Without core memories affixed to those photos, they are not nearly as valuable. The casino resort was crowded, the restaurants priced like Las Vegas, the waits long for almost anything. We had a lovely time together as a family, but almost nothing we snapped a photo of contributed to that time.

Dial into vacation elements that are important to you

When you’re trying to budget and plan for your summer vacation, come up with your cost ceiling first. See how much your proposed travel and accommodation costs eat into that number. If they almost reach your limit, maybe that version of the trip is too expensive. You want to leave room to experience the vacation, and those experiences will come at a cost.

In terms of what you choose to do, put yourselves at the center of those decisions. What will cause you to depart for home from your vacation saying, that felt really good?

Dial into the things that are important to you and your family — not what’s trending online. If you’re into food, focus on the food. If you’re into adventure, invest in that. When you set your itinerary with intention, you find the perspective you need to scale back on the superfluous things that cause you to overspend.

Finally, try putting your phone away or leaving it in the room, just for a little while. Tap into all five senses instead of diverting to some of your ordinary coping mechanisms. Nothing will be more memorable than trying, tasting or seeing something new that you don’t get in the ordinary course of your life.

Take it from us. We went away over the same weekend the following year to a beautiful, much more low-key resort on the beach. While there, we read whole books. Our phones lived in our bags. Our feet lived in the sand. Sure, we took photos, but we took more away from our time together than any photo-op would capture.

— By Heather and Douglas Boneparth of The Joint Account, a money newsletter for couples. Douglas is a certified financial planner and the president of Bone Fide Wealth in New York City. Heather, an attorney, is the firm’s director of business and legal affairs. Douglas is also a member of the CNBC Financial Advisor Council.

Don’t miss these insights from CNBC PRO

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XIAOHONGSHU Shines at VOGUE Business Global Beauty Summit

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Pioneering the Next Wave of Innovation in the Beauty and Personal Care Industry

NEW YORK, July 5, 2024 /PRNewswire/ — On June 25th, China’s leading social media and lifestyle platform, XIAOHONGSHU was invited to the VOGUE Business Global Beauty Summit. At the summit, XIAOHONGSHU joined over 100 beauty brand founders, executives, and industry experts to analyze the latest trends and discuss the future of the beauty industry. The event provided a platform to explore new marketing strategies for the international beauty market, particularly from a Chinese perspective, aiming to guide the industry towards a path of quality-driven development.

The summit featured Chujing, Head of Personal Care Department at XIAOHONGSHU, alongside over 100 global brand executives and marketing specialists from prestigious international companies such as LVMH Beauty, Kering Beauty, Estée Lauder, L’Oréal, P&G, Unilever, and Coty. Together, they discussed strategies to tap into and leverage local markets in the face of global trends, sparking new inspirations in BPC solutions and driving the global growth of brands.

Themed “Beauty Across Borders: Global Brands, Local Strategies“, the summit brought together key industry leaders, including Chujing; Anusha Babbar, Senior Vice President, Health & Wellbeing International at Unilever; and Shana Randhava, Senior Vice President, New Incubation Ventures at Estée Lauder. These executives engaged in a dynamic discussion about the rapidly evolving consumer demands in today’s BPC industry. They also explored strategies to help both domestic and international companies maximize their potential in the fast-changing market.

“Beauty Across Borders: Global Brands, Local Strategies” Panel
“Beauty Across Borders: Global Brands, Local Strategies” Panel

Trends Emerge, Beauty Ascends

XIAOHONGSHU Spearheads Exploration of New Opportunities in the BPC Industry

As consumer demand for beauty products continues to evolve, many BPC brands are focusing on how to anticipate and capitalize on emerging consumer trends to drive business growth. The 2024 China Beauty Industry White Paper released by XIAOHONGSHU identifies eleven key trends that are shaping the future of the beauty sector. The trends include technology-based skincare, the new focus on skin health, relaxed luxury, the rise of Eastern influences, makeup innovation, emerging product popularity, layered enhancements, cultural revitalization, advanced facial care, upscale beauty solutions, and at-home beauty treatments. The new trends are gaining momentum on XIAOHONGSHU, positioning the platform as a leader in the BPC industry and creating new opportunities for brands.

XIAOHONGSHU Identifies Four Major Drivers of Beauty Transformation

Elevating Groom & Bloom Lifestyle Group to New Heights

XIAOHONGSHU has identified four core drivers that enhance the Groom & Bloom lifestyle group centered around activities related to “being beautiful”: Self-empowerment, Personal Charisma, Demeanor, and Social Influence. Based on these pillars, XIAOHONGSHU has segmented Groom & Bloom lifestyle seekers into six major groups, providing fresh insights into the future growth and optimization of the BPC industry.

Self-empowerment | Wellness Seekers

For wellness seekers, life revolves around maintaining a set trajectory with an increasing awareness of the deep connection between physical beauty and overall well-being. They pursue holistic beauty and wellbeing, viewing beauty and skincare not just as a daily routine but also as a ritual of self-love

Personal Charisma | Trendy Explorers

Trendy Explorers are individuals, primarily in the initial phases of their growth, who are keen on experimenting with diverse looks. They explore and discover their personal potential and the variety of their charisma by trying different styles. Additionally, they draw inspiration from traditional culture, showcasing their unique oriental beauty in the Influence of Neo-Chinese Style scenarios.

Personal Charisma | Delicate Princess

Members of the Delicate Princess group are detail-oriented individuals, primarily unmarried and in the light-mature age. They have highly specific skincare needs, aspiring to embrace a lifestyle of Exquisite Beauty Care and Conveying Love.

Demeanor | Beauty Novice

Predominantly unmarried, this group focuses on adapting to and advancing their careers while navigating the initial stages of their professional lives. They are actively learning and practicing beauty and skincare techniques, with a focus on beauty learning as well as matched and appropriate beauty products.

Demeanor | Charismatic Elite

The Elite group is focused on building personal influence and expanding career possibilities as they ascend the career ladder. Their primary BPC needs revolve around appropriate demeanor, stable but open to experience, and balance and efficiency

Social Influence | Trend Setters

Trend Setters are individuals actively exploring new interests, typically childless and in the career advancement stage. They seek BPC products that incorporate pioneering beauty technology, influential aesthetics, and the art of fragrance.

By analyzing the unique motivations of various user demographics, XIAOHONGSHU’s Top 20 Lifestyle Groups enable brands to gain a deep understanding of consumers’ real lifestyles and consumption characteristics. This insight facilitates an efficient alignment of users, needs and products. The different Groom and Bloom groups not only drive new trends in the BPC industry but also offer fresh marketing insights to brands.

From Efficient Seeding to Comprehensive Conversion

XIAOHONGSHU Unveils a Three-Step Approach to Unlocking New Opportunities in the BPC Sector

As a natural seeding ground for brands, XIAOHONGSHU significantly influences users’ purchasing decisions. With its unique community ecology and effective seeding capability, the platform enables BPC brands to unlock countless marketing possibilities. To promote quality growth within the BPC industry, XIAOHONGSHU aids brands in optimizing their marketing efforts by providing them with a three-step marketing approach encompassing efficient seeding, brand enhancement, and comprehensive conversion.

During the product seeding phase, brands can quickly and profoundly impact their core audience through XIAOHONGSHU’s distinctive Reverse Funnel Audience Expansion. This model facilitates the expansion beyond the initial target demographic, enabling brands to rapidly unleash their potential and effectively manage their audience assets.

XIAOHONGSHU’s Reverse Funnel Audience Expansion
XIAOHONGSHU’s Reverse Funnel Audience Expansion

With its authentic and diverse content, XIAOHONGSHU has increasingly become a vital platform for user searches. The dedicated brand zone serves as a crucial marketing hub within the search realm, enhancing the conversion of content seeding by facilitating a deep connection between the target audience and the brand. Moreover, XIAOHONGSHU’s marketing IP stands out with its relatable topics, refined aesthetics, diverse content, and comprehensive resource support, all of which help brands quickly expand target audience and amplify marketing efforts. In addition, brands can leverage XIAOHONGSHU’s three conversion paths—on-site, off-site, and offline—to expedite the purchasing decisions of users and shorten the journey from interest to transaction.

Participating in the VOGUE Business Global Beauty Summit represents a significant step in XIAOHONGSHU’s efforts to expand its influence in the global BPC market. As a premier marketing platform for international BPC brands entering the Chinese market, XIAOHONGSHU remains committed to collaborating with more partners within the industry to stay at the forefront of emerging trends. Together, they will explore innovative marketing strategies and seek out the keys to quality growth.

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Xinhua Silk Road: Forum held in SW China Yunnan’s Yuxi to deepen international cooperation on Chengjiang Biota

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BEIJING, July 5, 2024 /PRNewswire/ — The “40th Anniversary, Discovery of Chengjiang Biota — International Palaeontological Forum” kicked off on July 2 in Chengjiang, Yuxi, Southwest China’s Yunnan Province, and will last to July 6.

The photo shows the site of the 40th Anniversary, Discovery of Chengjiang Biota -- International Palaeontological Forum. (Source: Yunnan.cn)
The photo shows the site of the 40th Anniversary, Discovery of Chengjiang Biota — International Palaeontological Forum. (Source: Yunnan.cn)

This international forum aims to look back on the cooperation results in recent years, share experience, and look forward to the future. By leveraging the strengths of domestic and foreign research institutions, the forum seeks to deepen international cooperation in scientific research.

Experts and scholars from China, the United Kingdom, the United States, the Republic of Korea and Switzerland, have attended the forum. A total of 39 oral presentations and six academic posters will be presented to focus on domestic and foreign research achievements in life evolution in the early Cambrian Age.

Located on the shores of Fuxian Lake in the central part of Yunnan Province, the Chengjiang Biota is known as a “world-class treasure trove for fossils”. On July 1, 2012, the Chengjiang Biota was inscribed on the UNESCO World Heritage List, becoming China’s first and Asia’s only fossil world natural heritage site.

To date, more than 20 phyla and over 300 species of rare Cambrian fossils have been discovered in the Chengjiang Biota, with 80 percent of them being new species. The Chengjiang Fossil Site World Natural Heritage Museum now has a collection of over 60,000 specimens.

Original link: https://en.imsilkroad.com/p/340963.html

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Zhejiang Doer Biologics Completes Enrollment of the Phase 1b/2a Trial Evaluating DR10624 in Obese Subjects with Modest Hypertriglyceridemia

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HANGZHOU, China, July 5, 2024 /PRNewswire/ — Zhejiang Doer Biologics Co., Ltd. (“Doer Bio”), a clinical stage biopharmaceutical company developing innovative biotherapeutics for metabolic diseases and cancers, today announces that the company has completed the enrollment in the Phase 1b/2a trial evaluating DR10624 in obese subjects with modest hypertriglyceridemia in New Zealand. DR10624 is a first-in-class (FIC), long-acting tri-specific agonist targeting Fibroblast growth factor 21 receptor (FGF21R), Glucagon-like peptide-1 receptor (GLP-1R), and Glucagon receptor (GCGR).

The Phase 1b/2a study is a randomized, placebo-controlled, double-blind study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of DR10624 in adult obese subjects (BMI of 30 to 45 kg/m2) with modest hypertriglyceridemia (fasting triglyceride ≥150 mg/dL (1.7 mmol/L), and <500 mg/dL (5.7 mmol/L), at screening). The study evaluates DR10624 treatment across four different dose levels. The participants will receive once-weekly subcutaneous injection of DR10624 or placebo (in a 10:2 ratio) for 12 weeks. The study will also evaluate the effects of DR10624 on serum lipids, liver fat, and body weight.

“DR10624 is a novel FIC tri-specific biotherapeutic that specifically agonizing FGF21R, GLP-1R, and GCGR. Utilizing Doer Bio’s proprietary MultipleBody® platform technology, DR10624 is designed and engineered to exhibit balanced activity for various metabolic diseases. In our preclinical studies, DR10624 has shown outstanding potency on body weight reduction, blood lipid normalization, and liver function improvement.” said Yanshan Huang, Ph.D., founder and Chief Executive Officer of Doer Bio.

“We’re excited to announce the successful completion of patient enrollment for our Phase 1b/2a clinical trial of DR10624 in New Zealand. This achievement marks an important milestone in our clinical translation of DR10624 globally. We anticipate reporting the trial results in early 2025. There is a growing unmet medical need for patients suffering from obesity and hypertriglyceridemia. We look forward to developing DR10624 as a potential treatment for patients struggling with metabolic dysfunction.” commented Yongliang Fang, Ph.D., Chief Operating Officer of Doer Bio.

More information about the Phase 1b/2a clinical trial is available at clinicaltrials.gov (NCT05378893)

About Doer Bio

Zhejiang Doer Biologics Co., Ltd. (“Doer Bio”) is a clinical stage biopharmaceutical company that focuses on the discovery and development of multi-domain based multi-specific biotherapeutics to address unmet medical need in the field of metabolic diseases and cancers.

Doer Bio has developed multiple proprietary platform technologies, including xLONGylation®, MultiBody®, AccuBody®, and SMART-VHHBody.

For more information about Doer Bio, please visit www.doerbio.com.

CONTACT: bd@doerbio.com

Source: Zhejiang Doer Biologics Co., Ltd.

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Safety first! This bestselling carbon monoxide detector is $20 for 4th of July

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For better or worse, the phrase “better safe than sorry” has become my motto as an adult. That means, among other things, carbon monoxide detectors on every floor — and they have to work! If you can’t remember the last time you replaced yours, it’s probably time for a new one. My recommendation? The No. 1 bestselling Kidde Carbon Monoxide Detector, which is portable enough to travel with. Plus, it’s currently marked down for Amazon’s 4th of July sale.

Oh, and speaking of Independence Day, you’ll definitely want to check out our roundup of the best 4th of July sales across the web to save even more.

Amazon

Tens of thousands of Amazon shoppers swear by this little lifesaver. 

$20 at Amazon

Why is it a good deal? 💰

You can’t put a price on safety, but $20 is extremely reasonable for a product that could literally save lives. This isn’t the absolute lowest price we’ve seen on this model, but it’s just about as low as we’ve seen it dip in the past year — nearly 40% off.

Why do I need this? 🤔

True story: Because I’m a safety obsessive, I check every hotel room and Airbnb I stay in to see whether there’s a carbon monoxide detector. Recently, I was at an Airbnb that only had smoke detectors. So what did I do? I went out and bought the Kidde Carbon Monoxide Detector.

It might seem a little extreme, but I’d rather err on the side of caution. Since this portable model is quite compact, I plan on keeping it in my suitcase juuust in case. After all, vacation is much more enjoyable with some peace of mind!

At under half a pound and 5 inches wide, the Kidde makes a smart travel mate, but it’s ideal for at-home use as well. It calls for two AA batteries (included) and can be mounted to a wall or placed on a table or other flat surface. To ensure it’s working, press the test button (it’s loud). The green light means it’s on, but a red light and beeping means you should go outside immediately.

This compact carbon monoxide detector comes with a 10-year limited manufacturer warranty, but you’ll want to make sure the batteries are always in working order. (Speaking of batteries: Because it doesn’t plug into an outlet, it’ll keep working during power outages.)

the Kidde carbon monoxide detector on an orange background

We’re not Kidde-ing around — a carbon monoxide detector is a must-have at home and on the go. (Amazon)

What reviewers say 💬

Over 25,000 Amazon customers are sleeping easier with the Kidde Carbon Monoxide Detector.

Pros 👍

“This product possibly saved my and the lives of my family,” shared one relieved shopper. “I decided to replace the ones I had mounted from several years ago; two weeks after and at 4 a.m., it began alerting near my boiler room. After having an army of plumbers come in, it was found that there was a CO leak from my old boiler that was not persistent, so it wasn’t at a level to set off my old alarm. It was explained that the issue was progressive and would have gotten worse, so the early alerting gave me an opportunity to address the problem before it got to a point where it could have caused real physical damage or possibly much worse.”

“We got this to take to Cozumel with us,” shared a savvy jetsetter. “It was very lightweight and easy to pack. I highly recommend taking one when traveling abroad. I don’t think you can ever be too safe.”

“My last one needed to be replaced after it started beeping due to age,” explained a repeat buyer. “Luckily, it was of the same brand, so this new detector went right back onto the same backplate, with no need to install the new one. Easy as pie. CO detectors are a must-have for anyone who has fossil fuel-based utilities, including a furnace, boiler, water heater or stove, and these are a great option.

Cons 👎

“One downside is that it does not have a screen,” wrote an otherwise thankful reviewer, “so at first I was hesitant whether it was actually beeping from detecting CO or low battery. … This product literally saved the lives of me and my two toddlers! We had a leak of carbon monoxide in our home from our standby generator, and by the time the fire department arrived and tested, they said the levels in our attic leaking down into our home from our generator were extremely dangerously high. Cannot explain in words how grateful I am for this quality product.”

“A must-have!” exclaimed a final fan. “I like that you can either hook it up on a wall or you can leave it on a different surface.” Their one note? “I wish it had a plug-in option.” (Psst: I also have this plug-in model in my house, though it’s less travel-friendly.)

Amazon

Safety first: Snag one of these for every floor of your home (and another for your travel bag) while it’s on sale.

$20 at Amazon

While we’re at it, need a new smoke detector?

Amazon

There’s no such thing as too many smoke detectors. At under $20 each, these battery-operated essentials should be a fixture in your home. 

“Very loud and extremely sensitive,” wrote a pleased user. “[It] goes off if I take something from the oven [that has] burnt food on it. You won’t have to worry about hearing them, for you will be notified in plenty of time to leave your house.”

$19 at Amazon

If you have Amazon Prime, you’ll get free shipping, of course. Not yet a member? No problem. You can sign up for your free 30-day trial here. (And by the way, those without Prime still get free shipping on orders of $25 or more.)

The reviews quoted above reflect the most recent versions at the time of publication.

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realme Unveils Its Ultra Clear Camera with AI, the realme 13 Pro Series, Pioneering a New Era in AI Imaging

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BANGKOK, July 5, 2024 /PRNewswire/ — realme, the world’s fastest-growing smartphone brand, today unveiled its highly anticipated ultra clear camera with AI, the realme 13 Pro Series, at the realme AI Imaging Media Preview Event in Bangkok.

Themed “The Future is Here: AI is Revolutionizing Mobile Imaging”, the media event saw industry leaders and experts come together to explore the transformative impact of AI on mobile imaging technology. Guests included Sven-Olaf Steinke, General Manager of Certification at TÜV Rheinland Greater China, who presented TÜV Rheinland’s latest insights on the innovation of mobile photography, and Toshimitsu Kurosaka, Vice President of Sony Semiconductor Solutions (Shanghai) Limited, who announced a new collaboration between Sony and realme via video presentation.

Through the collaboration between realme and Sony, the realme 13 Pro Series will see the debut of Sony’s LYT-701 sensor, promising exciting advancements in imaging experiences further empowered by realme’s industry-leading AI Photography Architecture, HYPERIMAGE+.

Revolutionizing Mobile Photography with AI

“We stand at the cusp of a revolution in mobile photography,” said Francis Wong, Head of Product Marketing at realme. “For years, the smartphone industry has been competing in a race to outdo each other in terms of imaging hardware — megapixels, sensors sizes, and lens technology. While smartphones continue to provide users with increasing flexibility and control over their shots, advancements in optical solutions have reached a limit. The future is not about hardware alone. AI is the new battlefield where the future of mobile photography will be decided.”

Marking the latest achievement in its AI innovation, realme has developed HYPERIMAGE+, the industry’s first AI photography architecture, featuring a three-layer architecture that consists of flagship optics, on-device AI imaging algorithms, and cloud-based AI image editing.

As the base layer of HYPERIMAGE+, cutting-edge optics consisting of multiple lenses, periscope lenses, and large sensors, form the foundation for advanced photography solutions capable of capturing high-quality image. Building upon this, AI imaging algorithms and AI image editing further process image data to enhance the visual quality of photo and video content. The new comprehensive approach takes mobile photography to new heights, enabling users to enjoy ultra clear camera with AI from the convenience of their smartphone.

Reconstructing Portrait Aesthetics with the realme 13 Pro Series

Powered by the HYPERIMAGE+ architecture, the realme 13 Pro Series, positioned as the Ultra Clear Camera with AI, boasts first-class optics and cutting-edge AI capabilities that together promise to deliver an experience on par with professional DSLR cameras. The realme 13 Pro+ features a dual main camera system, a 50MP OIS main camera with the industry-first Sony LYT-701, and a 50MP periscope telephoto camera with the Sony LYT-600, supporting 3x optical zoom. The advanced system enables the phones to deliver exceptional image quality in a wide range of scenarios, from low-light settings to stunning portraits.

“This collaboration is about more than just technology, it’s about empowering everyone to capture and share their world in ways never before imagined,” said Toshimitsu Kurosaka, Vice President of Sony Semiconductor Solutions (Shanghai) Limited.

By bringing AI capabilities to image processing in the RAW domain, realme’s AI HyperRAW Algorithm significantly boosts image clarity and dynamic range to capture authentic light and shadow with true-to-life results. The realme 13 Pro Series also features a series of advanced functions, including AI Pure Bokeh, AI Natural Skin Tone, and AI Ultra Clarity, which set a new benchmark for portrait photography. With AI Pure Bokeh, the camera is able to accurately identify foreground, midground, and background elements in a scene, as well as the subject being photographed, which is then used to perform pixel-level segmentation of objects and apply targeted algorithmic optimizations and processing to creating realistic cinematic portraits in seconds. AI Natural Skin Tone can enhance the natural appearance of various skin tones using on-device AI processing, while the cloud-based AI image editing feature AI Ultra Clarity can significantly enhance low resolution photos to deliver stunning quality images that overcome the physical constraints of the underlying camera hardware.

Ahead of its upcoming launch, the realme 13 Pro+ has also received the High Resolution Camera Certification by international independent third-party testing, inspection, and certification organization, TÜV Rheinland certification.

“No matter how mobile imaging evolves, clarity will always be the foundation,” said Sven-Olaf Steinke, General Manager of Certification at TÜV Rheinland Greater China. “From capturing the subtle glow of dawn and the soft light of streetlamps, to shooting intense sunlight in nature, the realme 13 Pro+ ensures exceptional image clarity in virtually any lighting environment.”

Underscoring realme’s commitment to popularizing AI and empowering young users to capture their world in a whole new way, the realme 13 Pro Series is scheduled to launch in India soon. Further details will be announced at the official launch event in India.

About realme

realme is a global consumer technology company disrupting the smartphone market by making cutting-edge technologies more accessible. It provides a range of smartphones and lifestyle technology devices with premium specs, quality, and trend-setting designs to young consumers. Established by Sky Li in 2018, realme has become one of the top 5 smartphone players in 30 markets globally in just three years, and realme has entered multiple markets worldwide, including China and Southeast Asia, South Asia, Europe, the Middle East, Latin America, and Africa, and has a global user base of over 200 million. 2024 is the year of rebranding for realme with its new slogan, “Make it real.” Under the new brand spirit, realme will focus more on young users than before and bring real, clear, and tangible benefits to their lives. For more information, please visit www.realme.com.

Contact: realmepr@realme.com

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10 Million Downloads and Counting: Suika Game Releases Special Skins Expansion Pack for Nintendo Switch users

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TOKYO, July 5, 2024 /PRNewswire/ — Aladdin X Inc. a subsidiary of the award-winning projector and laser projector brand XGIMI, launched the ‘[Summer Version] Special Skin Expansion Pack’ in Japan on June 28th. This new pack, now available globally, allows players to enjoy customizing the game interface by combining various parts on Nintendo Switch™.

[Summer Version] Special Skins Expansion Pack
[Summer Version] Special Skins Expansion Pack

Starting June 28th, we are offering a series of free skins that allow players to customize with favorite combination at no cost. Additionally, we have released four paid skins, each inspired by a delightful summer theme: ‘Sunset Beach’, ‘Sunflower Farm’, ‘Summer Holiday’ and ‘Fireworks display’.

These paid skins include multiple customizable parts (background, Poppy, box, and dressing up your own watermelon), allowing players to create a unique design. We hope you enjoy this new feature.

We are thrilled to announce that the total number of downloads for Suika Game across Nintendo Switch, iOS, and Android has exceeded 10 million. We remain dedicated to enhancing the gaming experience for all players, and we appreciate every of your continued support.

Suika Game – Free skins

Customize the combination of the game interface including, background, box, Poppy and more to your favorite combinations at no cost.

Suika Game - Free skins
Suika Game – Free skins

Suika Game – [Summer Version] Special Skins Expansion Pack (Paid)

We offer a collection of four summer-themed skins: ‘Sunset Beach’, ‘Sunflower Farm’, ‘Summer Holiday’ and ‘Fireworks display’.
The [Summer Version] Special Skins Expansion Pack, which contains all four skins, is now available on the Nintendo Switch eShop worldwide.
Price: 350 JPY / 4.19 USD / 4,19 EUR / 3,500 KRW / 21 HKD

Individual purchase options:

Sunset Beach: A summer sunset beach theme with 8 interchangeable fruit parts, a newly designed Poppy and box, and a tropical background skin.
Price: 100 JPY / 1.19 USD / 1,19 EUR / 1000 KRW / 6 HKD

Suika Game - Sunset Beach skin
Suika Game – Sunset Beach skin

Sunflower Farm: A sunflower farm theme with 8 interchangeable fruit parts, a newly designed Poppy and box, and a sunflower farm background skin.
Price100 JPY / 1.19 USD / 1,19 EUR / 1000 KRW / 6 HKD

Suika Game - Sunflower Farm skin
Suika Game – Sunflower Farm skin

Summer Holiday: A summer holiday theme with 8 interchangeable fruit parts, a newly designed Poppy and box, and a traditional Japanese garden background skin.
Price: 100 JPY / 1.19 USD / 1,19 EUR / 1000 KRW / 6 HKD

Suika Game - Summer Holiday skin
Suika Game – Summer Holiday skin

Fireworks display: A fireworks display theme with 14 interchangeable fruit parts, a newly designed Poppy and box, an animated fireworks festival-style skin, an animated firework effect game start interface, limited BGM inspired by summer festivals, and sound effects that play every time the fruit evolves.
Price: 150 JPY / 1.79 USD / 1,79 EUR / 1500 KRW / 9 HKD

Suika Game - Fireworks Display skin
Suika Game – Fireworks Display skin

* Nintendo Switch is a trademark of Nintendo.

About Suika Game

Suika Game is a puzzle game where players group fruits of the same type and gradually evolve them into larger fruits, with the highest-level being a watermelon.
Copyright: ©︎ 2021 Aladdin X Inc
Official Website: https://www.aladdinx.jp/pages/suika-game
Official X: https://twitter.com/SuikaGame_jp 

About XGIMI

XGIMI Technology Co., Ltd (688696.SH), established in 2013, is a global leading brand in projectors and laser projectors, integrates design, R&D, manufacturing, sales, and service. Cooperating with well-known partners like Google, Harman Kardon, and Texas Instruments, XGIMI strives to create all-in-one entertainment products and continuously refine them with a user-centric approach. In 2023, XGIMI ranked first in the global home projector market in terms of shipments.

Additional information is available at: https://www.xgimi.com/

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