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NSW schoolgirl declared cancer free after raising $200,000 for ovarian cancer research

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“I’m coming home tonight.”

These were the four words NSW girl Tirion Wilkinson uttered when she told her siblings she was free of stage four ovarian cancer.

The 11-year-old was diagnosed with ovarian cancer three days before Christmas.

Since then, she has endured four rounds of chemotherapy and three operations.

Ovarian cancer is rare in children, according to the Ovarian Cancer Research Foundation.

The disease is often not diagnosed until it is in late stages, which reduces the survival rate for adults to just 29 per cent, foundation CEO Robin Penty said.

But Tirion and her family received welcome news this week when a PET scan revealed she was cancer-free.

In a moving call with family, played on radio station 2GB, Tirion’s siblings ask: “Is the cancer all gone?”

“Yeah,” she says, as her family erupts into excited squeals and cheers.

Speaking to 7NEWS, Tirion said she was “relieved” when the doctor broke the news.

“I’m feeling good,” she said.

“I don’t have any more cancer.

“I’m really happy about it and excited.”

Dad Lyle Wilkinson said it was a hard road to get there.

“Her friends have been good and family … they’ve helped her through it,” he said.

“We’ve still got a bit of a road to go, but we’ll push through it and keep going.

“At the start of it when we found out with my daughter, we just knew we had to give 100 per cent and push on … so that’s what we did.”

Lighting up a nation

Unlike most ovarian cancers, Tirion’s was “exquisitely responsive” to chemotherapy.

“In adults that is not the case,” Penty said.

“Ovarian cancer is highly resistant to chemotherapy, and 80 per cent of women receive a recurrent diagnosis.”

Tirion made headlines last week when her best friend Chloe Mackenzie-Matteson shaved her head to raise money for the foundation’s research.

The pair had been joined at the hip with since they met in Year One at Yowie Bay Public School, with Chloe describing her best friend as “one of the best people I’ve met in probably my entire life”.

Chloe Mackenzie-Matteson and Tirion Wilkinson have been best friends since Year One.
Chloe Mackenzie-Matteson and Tirion Wilkinson have been best friends since Year One. Credit: 7NEWS

Together, the girls have raised more than $200,000 for the foundation, with the money to help fund research in detection, prevention and treatment of the cancer.

In adults, moving from adolescents and upwards, the five-year survival rate of ovarian cancer is 49 per cent, according to the Australian Institute of Health and Welfare.

“Most ovarian cancer diagnoses come in late stages, which reduces survival to 29 per cent,” Penty said.

“Funding for research for this generation and beyond is what’s needed to change that narrative.”

Penty said the girls’ donation was the single largest gift they had received from a community fundraiser.

“We’re over the moon and blown away by the power of these girls,” Penty said.

“We think they could light up a nation.”

Tirion said she was “really proud” of her and Chloe’s efforts in fundraising and raising awareness.

“Hopefully, it will help future women and girls to be let known earlier so they don’t have to go through the same thing as me in the future,” she said.

– With Sarina Andaloro

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Experience Family Paradise in Vietnam at Premier Residences Phu Quoc

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PHU QUOC, Vietnam, May 17, 2024 /PRNewswire/ — Nestled in the vibrant southern area of Phu Quoc Island, Premier Residences Phu Quoc Emerald Bay unveils its special summer offer at the ultimate resort for families seeking fun and creativity. Here, parents and children will have the chance to truly “live in style” throughout their vacation.

Premier Residences Phu Quoc Emerald Bay - Hero Image - Resort Overview
Premier Residences Phu Quoc Emerald Bay – Hero Image – Resort Overview

Family-Friendly Accommodation

Located at Kem Beach – one of the top 100 most beautiful beaches in the world, guests staying at Premier Residences Phu Quoc Emerald Bay can truly embrace the natural beauty of the “pearl island”. The resort offers a diverse accommodation system with 752 units from rooms, suites, apartments, penthouses and villas. Particularly, apartments, penthouses or villas with open living space and private swimming pools will be the ideal choice for families looking for privacy during the vacation.

Premier Residences Phu Quoc Emerald Bay - Main pool overview
Premier Residences Phu Quoc Emerald Bay – Main pool overview

Looking over the emerald private beach, the room system here always offers outstanding views from dawn till dusk. The interior of the rooms is designed in a contemporary and elegant style with white and blue as the main color scheme, inspired by the waves and fresh ocean breezes. Whether for small families or multi-generational ones, guests will find options that perfectly cater to their needs.

The resort offers numerous picturesque spots and impressive check-in locations for travelers. The standout feature that first captures the attention of visitors at Premier Residences Phu Quoc Emerald Bay is the main building, characterized by its unique and innovative architecture, drawing inspiration from the wooden barrels used by the island’s fishermen for fermenting fish sauce.

Premier Residences Phu Quoc Emerald Bay - Dining experiences
Premier Residences Phu Quoc Emerald Bay – Dining experiences

Exciting Entertainment Activities

The resort provides a wide range of classes and workshops for both adults and children with a focus on environmentally-friendly activities such as the Little Gardener program at the Kids Club or the souvenir-making workshops using recycled materials at the Playground. These programs allow children to have fun while learning about their love for nature, the ocean and animals.

Every Saturday afternoon, the resort hosts a lively and fun pool foam party. Guests can immerse themselves in the cool, refreshing water, play with the fluffy white foam, and enjoy joyful moments with family and friends.

Staying at the resort, guests can easily visit Sunset Town, one of the most popular destinations in Phu Quoc. The entire family can admire the radiant beauty of the Kiss Bridge at dusk and capture impressive check-in photos. When night falls, families can stroll and shop at the VuiFest Night Bazaar, featuring various colorful street performances. Especially, guests should not miss the multimedia performance masterpiece “Kiss of The Sea” and the nightly fireworks display.

Premier Residences Phu Quoc Emerald Bay - Family moments
Premier Residences Phu Quoc Emerald Bay – Family moments

Summer Offer

All room rates at Premier Residences Phu Quoc Emerald Bay include tickets to the “The Kiss of The Sea” show. Upon arrival, guests simply need to contact Reception to set up their FaceID ticketing data and head to Sunset Town to enjoy this spectacular performance.

Access our media kit for the full release HERE

Contact: 

Email: HB2Q9-RE1@accor.com 

Website: https://premierresidencesphuquoc.com/

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Troy Animal Healthcare Strengthens Quality Operations with Veeva Vault Quality

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Australian animal health leader adopts Veeva Vault QualityDocs and Veeva Vault Training for greater efficiency and compliance

SYDNEY, May 17, 2024 /PRNewswire/ — Troy Animal Healthcare and Veeva Systems (NYSE: VEEV) today announced Troy’s selection of Veeva Vault QualityDocs and Veeva Vault Training to simplify its compliance, content management, and data processes. Troy Animal Healthcare (Troy), the Australian-owned leader in animal healthcare and manufacturing will use Veeva Vault Quality applications to streamline and automate its operations, accelerating the development of novel drugs for animals.

 

“Harmonizing quality and GxP compliance processes will drive efficient quality management across our operations,” said Paul Barnett, CEO at Troy. “As the first animal health company in Australia to adopt Veeva Vault QualityDocs and Veeva Vault Training, we are introducing new standards for GxP management, compliance, and collaboration. This is a critical advancement as we continue to provide products for the unmet clinical needs in veterinary health.”

With Vault QualityDocs, Troy will modernize its GxP document control and SOP management with built-in industry best practices and standardization to ensure compliance. The company will also use Vault Training to develop and assign curriculum digitally, increasing visibility of training requirements. Using quality applications on a single cloud-based platform will increase productivity and GxP compliance while driving more effective audits and inspections.

“We are proud to partner with Troy to drive quality excellence across their operations in Australia,” said Chris Shim, general manager, Asia R&D and Quality at Veeva. “Veeva Vault Quality will provide a single source for content, streamlining quality processes and workflows to drive innovation across Troy’s animal welfare solutions.”

Vault QualityDocs and Vault Training are a part of Vault Quality Suite, bringing together quality processes, content, lab, and training management applications on a single cloud platform. To learn more, visit veeva.com/ap/VaultQuality.

About Troy Animal Healthcare 

Established 60 years ago by Australian Veterinarians, Troy Animal Healthcare is committed to delivering innovative, high quality, affordable animal healthcare solutions which meet the challenging and changing needs of veterinary professionals and animal owners. Our search for better clinical outcomes has been the source of our growth for the past 60 years and has been critical to our success. Troy prides itself on being an Australian owned business that meets the high standards of ethics and professionalism that is expected of us by the communities that we serve. Our vision is to be the largest Australian supplier of animal healthcare pharmaceuticals, and we believe that passionate, driven and innovative people are key to bringing this vision to life. For more information, visit troylab.com.au.

About Veeva Systems

Veeva is the global leader in cloud software for the life sciences industry. Committed to innovation, product excellence, and customer success, Veeva serves more than 1,000 customers, ranging from the world’s largest biopharmaceutical companies to emerging biotechs. As a Public Benefit Corporation, Veeva is committed to balancing the interests of all stakeholders, including customers, employees, shareholders, and the industries it serves. For more information, visit veeva.com.

Veeva Forward-looking Statements

This release contains forward-looking statements regarding Veeva’s products and services and the expected results or benefits from use of our products and services. These statements are based on our current expectations. Actual results could differ materially from those provided in this release and we have no obligation to update such statements. There are numerous risks that have the potential to negatively impact our results, including the risks and uncertainties disclosed in our filing on Form 10-K for the fiscal year ended January 31, 2024, which you can find here (a summary of risks which may impact our business can be found on pages 9 and 10), and in our subsequent SEC filings, which you can access at sec.gov.

 

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United Airlines says FAA cleared it to add new aircraft, routes after safety review

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A United Airlines 737 Max 8

Leslie Josephs | CNBC

United Airlines said the Federal Aviation Administration has cleared it to add new aircraft and routes months after the regulator stepped up its scrutiny of the carrier following several safety incidents.

“Today, we got some good news: after a careful review and discussion about the proactive safety steps United has taken to date, our FAA Certificate Management Office has allowed us to begin the process of restarting our certification activities, including new aircraft and routes, and we will continue to coordinate closely with the FAA,” United said in a note to employees Wednesday.

United said in March that the FAA had stepped up scrutiny of the airline after a spate of incidents earlier this year. That prevented it from launching new routes, including flights to Faro, Portugal, ahead of the busy summer travel season.

The clearance from the FAA is welcome news as United and other carriers expect a record peak season this year.

Among the safety incidents in recent months, a Japan-bound United Boeing 777 lost a tire shortly after takeoff from San Francisco in February, and a missing panel was discovered on a Boeing 737 after it landed in Oregon in March.

United said that it has more work to do, however.

“We will continue to see an FAA presence in our operation as they review our work processes, manuals and facilities,” it said in its employee memo.

The FAA didn’t immediately comment.

While the planes involved older jets, the incidents come amid heightened scrutiny of the aviation industry after a door plug blew out of a nearly new Boeing 737 Max 9 operated by Alaska Airlines earlier this year, a near catastrophe that has created a fresh crisis for the manufacturer.

Don’t miss these exclusives from CNBC PRO

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This long-handled shoe horn might make your life ‘so much easier’ — and it’s just $10

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If you have hip, knee or back pain, or are recently post-op, then tangling with shoes is anything but simple. However, thanks to the Vive Long-Handled Shoe Horn, you can put on or take off any shoe — sneaker, Croc, Oxford, you name it — while standing or sitting. At 24 inches high, the shoe horn works well for men and women, has a firm grip and is gently curved to slide into any size or style.

Amazon

After just one use you’ll be yelling, “Vive le shoe horn!”

$10 at Amazon

This shoe horn means you don’t have to wrestle with your Skechers or go toe-to-toe with your Hush Puppies. You can put on your shoes while standing up, which exerts less pressure on your muscles and joints — and lessens the chances of pulls and strains. And that can save you big bucks on medical costs.

The large oval handle gives you a safe and secure hold. Each edge is gently rounded to ensure it doesn’t snag on socks or stockings, or scuff your shoes. And as a handy extra, the handle allows it to be stored on a coat rack or storage hook for quick access. The durable plastic frame is sturdy and won’t crack or break, and the entire shoe horn can be separated into two pieces for traveling.

shoe horn

Never wrestle with your balance — or New Balances — again. (Amazon)

The lives of nearly 9,000 five-star reviewers have been made easier thanks to the “Best shoe horn,” as it was dubbed by this fan. “It’s exactly what I needed. I will soon have hip replacement surgery. To avoid extra bending and twisting immediately afterward, this shoe horn will aid me in getting shoes on. I have been practicing and find it easy to use. It is simple to assemble. It separates for traveling and is just the right height.”

As this shopper raved, “How could such a little thing, like a piece of plastic with a long handle make my life so much easier???” And this satisfied customer agreed: “I had knee replacement surgery last year and I am now going for a hip replacement on the same leg. With this shoe horn, I can now slide into my shoes alone. Extra benefit, I can get this horn inside of my socks and get them off, too!”

“It’s lightweight and I’m very pleased with it,” said this reviewer, “Only con might be that it’s plastic and therefore less solid or strong. But it’s strong enough, and if it were anything else it would lose its other benefits.”

“Better than what the hospital gave me,” revealed this satisfied customer. “After my hip replacement, the hospital gave me a ‘hip kit,’ which included a shoe horn. It was longer than the regular ones but still not long enough to keep me from having to bend over too far. So I searched until I found this one. It was here very quickly after I ordered it and has repeatedly proven to be just what the occupational therapist ordered.”

Amazon

It also comes with a sock remover tab so you can easily slip off your shoes AND socks.

$10 at Amazon

Psst: If your shoes are feeling a little too tight, Amazon shoppers also love this FootMatters Shoe Stretch spray:

Amazon

Just spritz some of this onto practically any shoe for some extra wiggle room — it also works on leather gloves!

$10 at Amazon

“In trying to figure out what my shoe size actually is now, I ended up with a couple of shoes that were just a smidge too tight,” revealed one reviewer. “This stuff really did the trick. I wore them over some chunky socks and used this spray, and in an hour or so they’d stretched enough that I could wear them comfortably. This is a lifesaver and a real money saver for any leather-esque shoes that aren’t quite fitting correctly.”

If you have Amazon Prime, you’ll get free shipping, of course. Not yet a member? No problem. You can sign up for your free 30-day trial here. (And by the way, those without Prime still get free shipping on orders of $25 or more.)

The reviews quoted above reflect the most recent versions at the time of publication.

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Sun Hats and Cooling Towels: The Perfect Combo for the Summer

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YIWU, China, May 16, 2024 /PRNewswire/ — As summer arrives in the Northern Hemisphere, sun hats and cooling towels become a perfect match. Although the summer’s heat hasn’t reached its peak, the early arrival of spring in China has noticeably advanced the sales schedule for sun protection products. Numerous merchants in Yiwu have observed a spike in sales, particularly for items such as sun hats, hats, and face-kinis since February 2024. Additionally, with the growing awareness of “national fitness”, high-tech sport gear like “cooling towels” are seeing a surge in sales.

Sun Hats and Cooling Towels on the www.yiwugo.com.
Sun Hats and Cooling Towels on the www.yiwugo.com.

Yiwugo.com, the official website of the Yiwu Commodity Market, is the largest commodity wholesale market in the world. According to big data from Yiwugo, from March 1, 2024, to May 12, 2024, the search volume rankings for keywords such as “hats” and “sun hats” has climbed from around the 40th place to around the 15th. During this period, the number of orders related to sun hats has remained nearly the same as in 2023, but the transaction value of these orders has increased by 1.65 times. Meanwhile, from April 1, 2024, to May 12, 2024, the number of orders related to cooling towels is 1.07 times that of 2023, with a year-on-year transaction value growth of 70%.

Mr. Zheng Xiongfeng, head of Yiwu Ruwei Clothing Co., Ltd., has been engaged in sports products such as towels and neck gaiters for many years. Seven years ago, he started producing cooling towels in response to customer demand. It was during this period that Disney buyers from Japan began cooperating with Ruwei, with the company exporting approximately 4 million cooling towels to Japan annually. This year, overseas orders came even earlier, with samples being prepared for clients as early as December 2023.

“Since 2022, the trend of sports fashion has been robust in China, and cooling towels have become popular in the domestic market,” Zheng said. By the end of April, there was a noticeable a surge in domestic orders for cooling towels. Anta, a well-known Chinese sports brand, chose Ruwei as its cooling towel supplier after a thorough selection process. The partnership has endured for over two years and continues to thrive.

In recent years, most of Ruwei’s new foreign orders have come from inquiries on the Yiwugo platform. As a leading manufacturer, Ruwei maintains a stockpile of 200 tons of raw materials for cooling towels in stock and oversees every step of the production process, from yarn procurement to fabric production and product cutting. This meticulous approach ensures control over every stage and fosters trust with clients, who often become long-term customers following sample evaluations and on-site inspections.

Hats remain a perennial industry in Yiwu, and this year’s sun protection season is no exception. Ms. Lou Shuhui and her Chengwen Hats Co., Ltd. have been in the business for nearly 20 years, primarily exporting baseball caps and bucket hats to over 30 countries, with an annual output value exceeding 50 million yuan. She noted an increase in orders from overseas brands this year. The company has been collaborating with Walmart for nearly six years, with annual transactions totaling around 2 million yuan. In 2021, they stood out among suppliers for Disney’s strict quality control on custom hats and have been working with them for three years, producing nearly 2,000 hats daily.

Another notable hat manufacturer, Fu Longnv, specializes in hats with UV protection materials. Her products, known for their SPF value, have a good reputation in the domestic market and the brand TUDROFI registered in the US has gained recognition in Europe and America. Since February, her company has been exporting outdoor sun hats with anti-slip buckles in black, white, navy, grey, and khaki. Customers frequently reorder every three days, and the company is busy with inquiries from foreign companies and buyers on the Yiwugo.

Haitao Hats Co., Ltd., a merchant in the Yiwugo industry belt, specializes in exporting fashionable yarn-dyed jacquard baseball caps. With an annual output of over 1 million caps, this 20-year professional hat manufacturer excels in fabric production, shaping machines, and the selection of lining and sweatbands. Currently, they are fulfilling a custom order for nearly 20,000 hats from a client in Tehran, Iran. In addition, they are discussing future cooperation after completing a trial order of hat brims customized by a procurement group from Guangzhou.

Amidst the scorching summer sun, sun protection products and cooling towels are in full swing for the peak season. Yiwugo stands out as the optimal platform for buyers seeking a wide array of best-selling products and reliable suppliers.

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Chemist Warehouse to lose discounted price of prescription medicine after Albanese government caves to pharmacy pressure

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The price of prescription medicine is set to rise after the influential Pharmacy Guild won a bid to strip Chemist Warehouse of its ability to offer customers $1 off medicines.

The federal government made the decision after negotiations with the pharmacy Guild came to a head.

WATCH THE VIDEO ABOVE: Government caves to pharmacy pressure to end a $1 script discount.

Often offering the lowest prices, Chemist Warehouse had previously used a policy allowing them to knock $1 off government-set prices on the cost of scripts to create competition — a policy that other pharmacies did not use.

The discount policy was first introduced by former health minister Sussan Ley in 2016, but now, the Albanese government has bowed to pressure from the Pharmacy Guild to end the days of discount scripts.

After the intense scrutiny of this year’s budget due to the rise in the cost of living, the Pharmacy Guild welcomed the decision — saying it will help Australians “struggling with the cost of healthcare”.

The lobby group fought for the change to the discounted scripts, saying it would keep costs down in the long run and “restore universality” to prescription prices but result in the binning of the $1 discount.

“The freezing of maximum medicine co-payments via the staged application of the discretionary $1 discount will help Australians struggling with the cost of healthcare and will restore universality to the PBS,” The Pharmacy Guild’s President Trent Twomey said.

The Pharmacy Guild said the measure will provide “much-needed relief” for those struggling to afford their essential medicines amid inflationary pressures and a cost-of-living crisis.

“Freezing indexation of co-payment means patients won’t have to foot more of the overall cost for their medicines come 1 January each year,” Twomey said.

“On behalf of our members, the Guild has a strong track record of fighting to bring down the cost of medicines — I’m pleased the Guild secured anti-inflationary relief for patients by phasing in the universal application of the $1 discount as part of our 8CPA negotiations.”

Chemist Warehouse has been contacted for comment.

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Hilton Properties Nationwide Unveils Month-Long National Wedding Sale

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Exclusive 20% discounts, lucky draw prizes and memorable perks await couples

KUALA LUMPUR, Malaysia, May 16, 2024 /PRNewswire/ — Hilton properties across Malaysia are pleased to announce the Weddings at Hilton. Whether you’re planning an intimate gathering or a lavish affair, let Hilton properties in Malaysia make your special day truly unforgettable.

Hilton Kuala Lumpur
Hilton Kuala Lumpur

The festivities commence with an exclusive 20% discount on selected wedding packages, Hilton Honor bonus points as well as additional perks from selected wedding partners. For convenience and easy bookings, the online wedding sale was launched on 6th May and will commence till 30th May 2024. Guests are encouraged to take the opportunity to enjoy great savings on this limited time offer via visiting weddingsathilton.com 

DoubleTree by Hilton Damai Laut Resort
DoubleTree by Hilton Damai Laut Resort

For those looking for customized packages and arrangements, the much-anticipated KLPJ Wedding Fair awaits from May 17th to May 19th, Booth B85, Hall 3 at Mid-Valley Exhibition Center. From start to finish, Hilton wedding specialists ensure a stress-free stroll down the aisle. Furthermore, booking made during the wedding fair comes inclusive of perks such as a complimentary stay in the Bridal Suite, customizable menus and food tasting just to name a few. Couples will also earn double Hilton Honors Points, which can be used to redeem a honeymoon at any Hilton hotel worldwide.

DoubleTree by Hilton Kuala Lumpur
DoubleTree by Hilton Kuala Lumpur

Hilton Kuching
Hilton Kuching

Attendees at the fair will have the chance to win lucky draw prizes from exclusive vendors which include complimentary pre-wedding cinematography by Motion In Style Production, a 2-hour 360 video booth service by TagBooth Photobooth, or a studio photoshoot by Precious. Additionally, all participants, regardless of their deposit amount, will receive a goodie bag with edible gift favors, cash vouchers, promotional materials, and a chance to win a 2-tier wedding cake by Sylvia Alexa Artistry.

Participating Hilton Properties:

Hilton Kuala Lumpur
Hilton Petaling Jaya
Hilton Kuching
Hilton Kota Kinabalu
Doubletree by Hilton Kuala Lumpur
Doubletree by Hilton Putrajaya Lakeside
Doubletree by Hilton Melaka
Doubletree by Hilton Johor Bahru
Doubletree by Hilton Shah Alam i-City
Doubletree by Hilton Damai Laut Resort
Doubletree Resort by Hilton Penang
Hilton Garden Inn Puchong

Wedding Partners:

Arifah Hot Oven
Sylvia Alexa Artistry
Armadale Weddings
Precious Wedding & The Gown Atelier
Mohan’s Executives Tailors
Momento Wedding
Motion In Style
TagBooth Photobooth
Posterlite
Merry Ice Cream

Book your wedding package during this month-long celebration of love and embark on a journey that will leave cherished memories for a lifetime. For more information, visit weddingsathilton.com.

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EHA 2024 | Results from Five Studies of Ascentage Pharma’s Key Drug Candidates Selected for Presentations at 2024 European Hematology Association Hybrid Congress

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SUZHOU, China and ROCKVILLE, Md., May 16, 2024 /PRNewswire/ — Ascentage Pharma (6855.HK), a global biopharmaceutical company engaged in developing novel therapies for cancer, chronic hepatitis B (CHB), and age-related diseases, announced today that the latest results from five studies have been selected for Poster Presentations at the 2024 European Hematology Association Hybrid Congress (EHA 2024). These posters will feature olverembatinib (HQP1351), the first and only China-approved third-generation BCL-ABL1 inhibitor; investigational lisaftoclax (APG-2575), a Bcl-2 selective inhibitor; and investigational APG-5918, an EED selective inhibitor.

The European Hematology Association (EHA) Hybrid Congress is the largest gathering of the hematology field in Europe. It showcases the most cutting-edge research and state-of-the-art innovative therapies, attracting over 10,000 clinical experts and researchers from more than 100 countries every year. This year, the EHA Hybrid Congress will take place on June 13 – 16, 2024, in Madrid, Spain.

“I am delighted to showcase the strength and progress of Ascentage Pharma in hematology at this year’s congress, especially the therapeutic potential and clinical value of its drug candidates in chronic myeloid leukemia (CML), Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), multiple myeloma (MM), immunoglobulin light-chain (AL) amyloidosis, and anemia diseases,” said Dr. Yifan Zhai, Chief Medical Officer of Ascentage Pharma. “We look forward to sharing the detailed results at the congress. In the future, we will continue to advance those development programs in efforts to bring more treatment options to patients around the world.”

The five studies to be presented at EHA 2024 are as follows:

  • Olverembatinib

Olverembatinib Overcomes Ponatinib and Asciminib Resistance in Patients (Pts) with Heavily Pretreated Chronic Myeloid Leukemia (CML) and Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph ALL)

•    Abstract#: P722
•    Presentation Type: Poster presentation
•    Topic: Chronic myeloid leukemia – Clinical
•    Date & Time: Friday June 14, 2024, 18:00 – 19:00 CEST
•    Presenting Author: Dr. Elias Jabbour, The University of Texas MD Anderson Cancer Center

Combination of Third Generation TKI Olverembatinib and Chemotherapy or Blinatumomab for New Diagnosed Adult Ph+ ALL Patients

•    Abstract#: P427
•    Presentation Type: Poster presentation
•    Topic: Acute lymphoblastic leukemia – Clinical
•    Date & Time: Friday June 14, 2024, 18:00 – 19:00 CEST
•    Presenting Author: Junjie Chen, Nanfang Hospital, Southern Medical University

Patient Reported Outcomes in Adults with TKI-Resistant Chronic Myeloid Leukemia Receiving Olverembatinib-Therapy

•    Abstract#: P1862
•    Presentation Type: e-Poster presentation
•    Topic: Chronic myeloid leukemia – Clinical
•    Date & Time: Friday June 14, 2024, 18:00 – 19:00 CEST
•    Presenting Author: Lu Yu, Peking University People’s Hospital

  • Lisaftoclax

Lisaftoclax (APG-2575) Combined with Novel Therapeutic Regimens in Patients (Pts) with Relapsed or Refractory (R/R) Multiple Myeloma (MM) or Immunoglobulin Light-Chain (AL) Amyloidosis

•    Abstract#: P917
•    Presentation Type: Poster presentation
•    Topic: Myeloma and other monoclonal gammopathies – Clinical
•    Date & Time: Friday June 14, 2024, 18:00 – 19:00 CEST
•    Presenting Author: Dr. Sikander Ailawadhi, Mayo Clinic Florida

Embryonic Ectoderm Development (EED) Inhibitor APG-5918 Improves Chronic Kidney Disease- (CKD)-Induced Hemoglobin (HB) Insufficiency in Preclinical Models of Anemia

•    Abstract#: P1550
•    Presentation Type: Poster presentation
•    Topic: Enzymopathies, membranopathies and other anemias
•    Date & Time: Friday June 14, 2024, 18:00 – 19:00 CEST
•    Presenting Author: Dr. Eric Liang, Ascentage Pharma Group Inc.

About Ascentage Pharma

Ascentage Pharma (6855.HK) is a globally focused biopharmaceutical company engaged in developing novel therapies for cancers, chronic hepatitis B, and age-related diseases. On October 28, 2019, Ascentage Pharma was listed on the Main Board of the Stock Exchange of Hong Kong Limited with the stock code 6855.HK.

Ascentage Pharma focuses on developing therapeutics that inhibit protein-protein interactions to restore apoptosis, or programmed cell death. The company has built a pipeline of 9 clinical drug candidates, including novel, highly potent Bcl-2, and dual Bcl-2/Bcl-xL inhibitors, as well as candidates aimed at IAP and MDM2-p53 pathways, and next-generation tyrosine kinase inhibitors (TKIs). Ascentage Pharma is also the only company in the world with active clinical programs targeting all three known classes of key apoptosis regulators. The company is conducting more than 40 Phase I/II clinical trials, including 5 global registrational phase III studies, in the US, Australia, Europe, and China. Ascentage Pharma has been designated for multiple Major National R&D Projects, including five Major New Drug Projects, one New Drug Incubator status, four Innovative Drug Programs, and one Major Project for the Prevention and Treatment of Infectious Diseases.

Olverembatinib, the company’s core drug candidate developed for the treatment of drug-resistant chronic myeloid leukemia (CML) and the company’s first approved product, has been granted Priority Review Designations and Breakthrough Therapy Designations by the Center for Drug Evaluation (CDE) of China National Medical Products Administration (NMPA). To date, the drug had been included into the China 2022 National Reimbursement Drug List (NRDL). Furthermore, olverembatinib has been granted an Orphan Drug Designation (ODD) and a Fast Track Designation (FTD) by the US FDA, and an Orphan Designation by the EMA of the EU. To date, Ascentage Pharma has obtained a total of 16 ODDs from the US FDA and 1 Orphan Designation from the EMA of the EU for 4 of the company’s investigational drug candidates.

Leveraging its robust R&D capabilities, Ascentage Pharma has built a portfolio of global intellectual property rights and entered into global partnerships with numerous renowned biotechnology and pharmaceutical companies and research institutes such as UNITY Biotechnology, MD Anderson Cancer Center, Mayo Clinic, Dana-Farber Cancer Institute, MSD, and AstraZeneca. The company has built a talented team with global experience in the discovery and development of innovative drugs and is setting up its world-class commercial manufacturing and Sales & Marketing teams. One pivotal aim of Ascentage Pharma is to continuously strengthen its R&D capabilities and accelerate its clinical development programs, in order to fulfil its mission of addressing unmet clinical needs in China and around the world for the benefit of more patients.

Forward-Looking Statements

The forward-looking statements made in this article relate only to the events or information as of the date on which the statements are made in this article. Except as required by law, Ascentage Pharma undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events, or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this article completely and with the understanding that our actual future results or performance may be materially different from what we expect. In this article, statements of, or references to, our intentions or those of any of our Directors or our Company are made as of the date of this article. Any of these intentions may alter in light of future development.

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Stanley who? I’m a shopping editor who hates drinking water — unless it’s from an Owala bottle

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I have a confession: I’m not a big fan of water. To my doctor’s chagrin, I prefer coffee, tea and various sugary drinks. In fact, I can’t remember the last time I hit the recommended hydration goal (which, according to the National Academy of Medicine, is nine cups of water per day for women over 19). That said, I also enjoy going to the gym, and the plastic water bottles I kept buying for $2 to $5 a pop were adding up — and not very good for the planet, either. So, I put on my deal-hunter hat, determined to find the best reusable water bottle. Reader, I found it: Say hello to the Owala FreeSip.

Amazon

This sleek bottle comes in four sizes (16, 24, 32 and 40 ounces), and the 24-ounce is narrow enough to fit in most car’s cup holders. 

$25 at Amazon

It’s weird to describe a water bottle this way, but I’ll say it: The Owala FreeSip is gorgeous. It was hard to pick just one hue — all 20 colors are equally stunning — but I chose Iced Breeze. First impressions aside, it’s not too different from most other quality chuggers: It has the same stainless steel body, powder-coat exterior and carry loop for easy transport.

It’s easy to dismiss the FreeSip as a bottle that prioritizes form over function, but don’t let looks deceive you. To experience its magic, you have to pop open the lid. It’s called the FreeSip for a reason. The dual-purpose spout allows you to sip or chug your drink without having to switch lids or remove the top. Want to take a swig? You got it, thanks to the wide mouth opening. Prefer to take it slow? Use the built-in straw. Can’t make up your mind? You can technically use both, but I would advise against it (unless you want to get water all over your face and shirt). I’d even argue that having two ways to get your daily water makes it more fun to hit those intake goals — it works for me, anyway.

White Owala water bottle on a bench.

See? Told you the Owala is gorgeous. (Izabella Zaydenberg/Yahoo)

It’s safe to say that I’ve put this water bottle through its paces. It’s been flipped upside down in my gym bag and knocked off the kitchen counter by my cat. It’s even rolled around the back seat of a car during hours-long drives. I’ve never seen a drop of water escape it. I have the bottle’s thoughtfully designed locking cap to thank for that: It has a push-button opening that feels more secure than a traditional twist lid. Once I hear that click, I know spills won’t destroy my bag or floor. Take that, Stanley. Speaking of…

The Owala FreeSip and the Stanley Quencher are both veritable social media catnip, but they’re not interchangeable.

For starters, there’s a price difference. The 40-ounce Owala FreeSip rings in at $38, while the Stanley Quencher is $45 for the same size. The discrepancy holds true for smaller sizes as well — the 32-ounce Owala is $33 while the Stanley is $35. The 24-ounce Owala is $28, Stanley’s 20-ounce tumbler is $30. Owala’s bottles also frequently go on sale.

The Owala and the Stanley are fairly similar in terms of aesthetics: Both are stainless steel, have a matte finish and come in a ton of cute colors. And when it comes to temperature retention, they both keep your water cold for up to 24 hours.

The biggest difference is spill resistance. The FreeSip can be flipped upside down without leaking. If you do that with the Quencher, its contents will pour out of the straw. If you’re still undecided, our Commerce Manager has waxed poetic about the Stanley. We’ll leave the decision up to you.

Owala FreeSip water bottles in colors Denim, Camo Cool and Dreamy Field.

PSA to my partner: For my birthday, get me an Owala in every color. (Amazon)

I’ve remained faithful to my Owala FreeSip for the last few months, and I really can’t see myself going back to any of the other bottles I’ve tried. It’s stood up to a reasonable amount of wear and tear, but it still looks brand-new. Most importantly, I find myself reaching for my water bottle over bad-for-me drinks more often. And hey, anything that can make water a little less boring is a win in my book.

I’m far from the FreeSip’s only fan. Aside from its massive TikTok fanbase, the bottle has amassed a huge following among Amazon shoppers; in fact, it’s the retailer’s No. 1 bestselling insulated water bottle, with more than 36,000 reviewers having given it a perfect five-star rating.

One fellow fan (who called the Owala “the hottest on the market”) wrote: “I would argue these are better than Stanley’s or anything out there. I prefer to have a mouthpiece that doesn’t require a straw sticking out. The big 40-ounce bottle is perfect for working out.”

I totally agree with this reviewer’s claim that the bottle’s straw design is “… pure genius. I usually sip mindlessly while working or driving, and not having to crane my neck for every gulp is a game changer. … This bottle also takes ‘hydration hero’ seriously. My water stays refreshingly chilly for hours, even on scorching days. No more lukewarm disappointments — just consistent, cool sips of satisfaction.”

This final reviewer may have put it best, if a little sadly: “My girlfriend is a nurse, and she loves this bottle more than she loves me. I think the promise [of] further Owala bottles is the only reason she’s sticking around at this point.”

Owala

Flip it, twist it, shake it: No matter how rough you are on your Owala, it won’t leak.

$28 at Amazon

The reviews quoted above reflect the most recent versions at the time of publication.

If you have Amazon Prime, you’ll get free shipping, of course. Not yet a member? No problem. You can sign up for your free 30-day trial here. (And by the way, those without Prime still get free shipping on orders of $25 or more.)

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