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Inaugural ‘Korea Medical Innovation Research Forum’ regular seminar, a success

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  • To be registered as an official research organization by the National Assembly Secretariat… Expected to become Korea’s leading medical think tank
  • Planning to initiate global multinational clinical projects in digital therapeutics
  • Establishing a future medical system centered around prevention and management… Expanding digital medical services

SEOUL, South Korea, April 19, 2024 /PRNewswire/ — Amid growing concerns about a medical crisis as a result of acute conflict between the government and the medical community due to an increase in the quota of medical school admission, the regular seminar of the Korea Medical Innovation Research Forum (KMIRF) kicked off; experts from various fields of the medical field gathered to prepare for future medical reform. It was held at Andaz Seoul Gangnam on the 17th of April.

First ‘Korea Medical Innovation Research Forum’ regular seminar
First ‘Korea Medical Innovation Research Forum’ regular seminar

KMIRF was launched last March by experts in various fields of the medical industry, and is co-represented by Dae Hee Kang, former dean of Seoul National University College of Medicine, current president of the Telemedicine Society, and Jong Yoon Lim, former chairman of the Bio Association, registered director of Hanmi Science and chairman of COREE Group.

Medical experts who serve as steering and working committee members of each division, including co-representatives Dae Hee Kang and Jong Yoon Lim, gathered and led a heated discussion for medical reform. In addition, the newly elected People Power Party Representatives Cheolsoo Ahn, Soomin Park, and Democratic Party Representative Do-geol Ahn (via video conference) attended and advocated the Forum at the National Assembly level.

Co-representative Jong Yoon Lim mentioned the urgency of addressing immediate medical reform in his opening speech and said, “Medical intellectual property rights belong to the country and the people, and in order to improve the country’s global competitiveness and future value in medicine, we need to go beyond Healthcare 4.0 and create a national and permanent proposition.” “We will definitely propose future medical innovation policies,” he said. “We plan to hold regular seminars for KMIRF at least six times a year and frequently put forward future medical innovation policies with the cooperation of experts and policymakers in each field.”

In his congratulatory address, Rep. Cheolsoo Ahn said, “The paradigm of health care has completely changed through COVID-19, and now, as part of medical reform, we need to establish a ‘future-oriented legal system’ that recognizes upcoming technological and social changes, and eliminates regulations that may become obstacles in advance.” He emphasized, “It is time to play a role in preparing ahead for the future,” and added, “I hope that KMIRF will be play a central role for this change.”

Co-representative Dae Hee Kang emphasized the importance and revitalization of digital healthcare and personalized preventive medicine through a presentation on the topic of ‘Future Medicine and Digital Healthcare’, as well as laying out the purpose and role in the establishment of KMIRF along with future goals. He also explained the operation plan and said, “We plan to register as an official research group within the National Assembly Secretariat and will fulfill our role as Korea’s representative medical think tank.” Industrial Division Director Mahn Soon Hwang gave a presentation on ‘Bio-Industry Trends’ and emphasized the importance of the country, companies, and investments for the development of the bio-ecosystem and medical reform.

In addition, a free discussion was commenced in relation to digital health, especially digital therapeutics, as with new therapeutics. It was suggested that regulatory bodies should be able to determine the price and fee structure that will compensate private companies for their enormous investment in clinical research at the time of approval, and came to a consensus that the tone should be set globally in which any country applying for clinical trials or regulatory approval should be adequately recompensed according to such profit structure logic. As the first step in accomplishing this vision, we have decided to pursue a project regarding multi-national digital therapeutics’ clinical trials around the world.

Hee Hwang, CEO of Kakao Healthcare, expressed his encouragement by saying that he deems it as a very timely strategy and said, “As a healthcare expert, I will utilize my expertise to help with the research group’s first project.”

Hong Taek Yong, a professor at Hanyang University (former 1st Vice Minister of Science and Technology), said, “I am looking forward to the role of Hanyang University at a time when innovative policies need to be promoted in order to incorporate the remarkable advancements in science and technology into healthcare, and I will do my best to contribute as a member.”

Professor In Taek Lim of Catholic University (former Director of the Health and Medical Policy Office of the Ministry of Health and Welfare) said, “In order to effectively respond to the rapidly changing medical environment and technological changes, our medical system must develop into human-centered digital-based medical care, and the launch of KMIRF at this time is critical.” “We will strive to ensure that the research committee stands at the center of this,” he said.

Meanwhile, the KMIRF aims to create a healthcare ecosystem where the government, medical community, companies, and citizens can coexist, establishing a future healthcare system centered around prevention and management, and resolving intergenerational and regional medical service imbalances through digital medicine, and other platforms. It will be a proponent in presenting ways to expand access to medical services. In addition, it plans to serve as a bridge through which medical policymakers and decision-makers can come together to commonly recognize and empathize with the all related policies that are put forth.

KMIRF is comprised of policy, human resources, and industry divisions; while Hong Taek Yong, former 1st Vice Minister of Science and ICT, leads the policy division, Yu Mi Seo, former 11th director of the Korea Education and Research Information Service, heads the human resources division, and Mahn Soon Hwang, current CEO of Korea Investment Partners leads the industrial division. 

First ‘Korea Medical Innovation Research Forum’ regular seminar
First ‘Korea Medical Innovation Research Forum’ regular seminar

First ‘Korea Medical Innovation Research Forum’ regular seminar
First ‘Korea Medical Innovation Research Forum’ regular seminar

[Appendix] Korea Medical Innovation Research Forum Steering Committee

Name

Profile

Dae Hee Kang

Former Dean of Seoul National University College of Medicine / Current President of the Telemedicine Society

Jong Yoon Lim

Former Chairman of the Bio Association / Current Chairman of COREE Group / Current Internal Director of Hanmi Science

Hong Taek Yong

Former First Vice Minister of Science and ICT / Current Professor at Hanyang University

In Taek Lim

Former Director of Health and Medical Policy, Ministry of Health and Welfare / Current Research Professor, Graduate School of Health and Medical Management, Catholic University of Korea

Oh Sang Kwon

Former Deputy Director of the Ministry of Food and Drug Safety / Current Visiting Professor at Seoul National University

Kil Won Kim

Current President of Korea Medical Biotechnology Association

Yu Mi Seo

Former 11th Director of Korea Education and Research Information Service

Jong Il Kim

Current Dean of Department of Medical Sciences, Seoul National University

Yoo Suk Hong

Current Dean of College of Engineering, Seoul National University

Mahn Soon Hwang

Current CEO of Korea Investment Partners

Sung Kwan Jung

Current Medical Vice Chairman of the Korean Hospital Association / Chairman of the Board of Directors of Our Children’s Hospital, Our Children’s Medical Foundation

Byung Ho Nam

Former Professor at Boston University / Current CEO of Herings, Co. Ltd.

Hee Hwang

Current CEO of Kakao Healthcare

Young Shin Lee

Current CEO of Seers Technology

Sung Jun Han

Current CEO of Avixgen, CTO of Dx&Vx

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Washington state travel guide: Breathtaking national parks, the bustling city of Seattle and beyond

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Washington state is known for its wide range of stunning natural landscapes, from rugged coastlines to snow-capped mountain peaks to vibrant rainforests.

Cities like Seattle and Spokane offer their own array of cultural and culinary attractions.

Whether you are interested in outdoor adventure or simply taking in the scenery, the Evergreen State has something for every type of traveler.

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Here’s a deep dive.

National Parks in Washington

Olympic National Park

Olympic National Park spans 70 miles of coastline and almost 1 million acres. This World Heritage Site and International Biosphere Reserve offers anything you could want from a national park, like hiking, boating and the opportunity to see wild animals in their natural habitat in the temperate Hoh Rain Forest.

“It’s one of those places that really embodies what you would consider the Evergreen State,” Jennifer Coleman, publisher of the Scenic Washington road trip guidebook and the road map for Washington state, told Fox News Digital during a phone interview. “The beaches along the Pacific there are pretty wild. So, I always tell people, bring a raincoat and plan for wind. You know, it’s not like going to the beach even in Oregon, where you can really lay out in the sun.”

“I mean, OK, we do get sunny days, but it’s just not the same as a little further south,” Coleman added.

Visitors can observe ecosystems in miniature in the tide pools of Olympic National Park’s beaches. And while there might not be many sunbathers, the park is a well-known destination for stargazers. About 95% of the park is designated as wilderness and is devoid of human-caused light, making for a spectacular view of the night sky.

Sunlight reflects off the blue surface of Diablo Lake, which sits at the foot of mountains in Washington's North Cascades National Park

Diablo Lake is one element of Washington state’s North Cascades National Park that draws tens of thousands of visitors each year. Park-goers can take canoes or kayaks out on the water to experience the lake’s beauty up close. (Giulio Andreini/UCG/Universal Images Group via Getty Images)

North Cascades National Park

This park is named for the many waterfalls along its hundreds of miles of trails. The clear, blue mountain waters of Lake Diablo and the park’s other lakes and rivers offer opportunities for boat tours and fishing and make North Cascades Coleman’s favorite of the state’s three national parks.

She pointed out that although the park is remote, its beauty is accessible to those not up for a hike, since a driving trip along the North Cascades Scenic Highway still affords gorgeous views of mountain peaks, verdant trees and rushing waterfalls.

And for those who want a hands-on experience, North Cascades National Park is known for its climbing opportunities.

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Naturalists can keep their eyes peeled for the gray wolves, wolverines and more than 200 species of birds that call one of Earth’s most diverse ecosystems home.

Mount Rainier National Park

“It’s sort of the iconic Washington thing, to go to Mount Rainier National Park,” Coleman said. The mountain lies along several officially designated scenic byways for the road trippers out there, and it is the highest peak in the Evergreen State, rising 14,410 above sea level.

Since the park is so highly attended, a timed entry system will be implemented during the busiest months, from May to September, beginning in 2024. Reservations open 90 days in advance.

NATIONAL PARK WEEK: 15 SURPRISING FACTS ABOUT AMERICA’S PARKS YOU MAY NOT KNOW

This is the most popular state park for mountain climbing and skiing, with more than 20 climbing routes and ski descents. With its wilderness backpacking campsites and more than 260 miles of maintained trails, including some that are paved, hikers of all stripes can find the perfect trek. 

Winter sports are popular in Mount Rainier National Park, but it is also known for its hundreds of species of wildflowers that bloom spectacularly over the summer.

Seattle, Washington

Washington’s largest city is also one of its main travel destinations and serves as the origin point for many of the road trips in Scenic Washington’s guides. The city itself offers plenty to do.

Seattle is known for shellfish and coffee

The Emerald City is known for its food and drink scene: Japanese cuisine, craft beer, wine and especially coffee and seafood.

Starbucks is based in Seattle, so naturally, the Starbucks Reserve Roastery is located there, too. Think Willy Wonka’s chocolate factory but for coffee, complete with a coffee bean library. Numerous smaller cafés are spread across the city as well for those who want a more unique espresso experience. 

Tea houses and bakeries are in no short supply, either, in case you need to cool it on the caffeine.

Seattle sits on Puget Sound, where shellfish are readily available. The city is known for its oysters.

Seattle's waterfront and city skyline are seen, including the iconic Great Wheel and Space Needle

Seattle’s waterfront is seen here, including the Great Wheel and the Space Needle. Seattle’s name is derived from the Native American name “Sealth,” who was a chief of the Suquamish tribe at the time the first White settlers arrived in 1851. (Mark Boster/Los Angeles Times via Getty Images)

Iconic Seattle attractions

Visitors to Seattle can stop at one of its many museums, like the Museum of Pop Culture, or look for the Fremont Troll, a giant sculpture under the George Washington Memorial Bridge. The colorful, if a bit gross, Gum Wall near Pike Place Market is worth seeing, and the market is itself well-known for its craftspeople, restaurants and fishmongers.

But few Emerald City attractions are more iconic than the Space Needle. The Space Needle was originally built for the 1962 World’s Fair and has become perhaps the most recognizable element of the city skyline. In just 43 seconds, you can ride the elevator all the way to the observation deck, where you can see far and wide over the rest of Seattle.

Few Emerald City attractions are more iconic than the Space Needle.

Across the street from the Space Needle is Chihuly Garden and Glass, home to the works of renowned glass artist Dale Chihuly. The breathtaking installations make this TripAdvisor’s top-rated Seattle attraction.

If the Space Needle is the most iconic component of Seattle’s Skyline, the Great Wheel is No. 2. This Ferris wheel was built in 2012 and offers a different way to get a bird’s eye view of the city and the surrounding mountains.

The Amazon Spheres provide an unexpected break from the hustle and bustle of the city with their four-story jungle-like interior, containing more than 40,000 plants. Another Washington-based company, Amazon, constructed the spheres to afford employees the tranquility of the rainforest without leaving the city. The Spheres are open to the public for free during the first and third Saturday of each month.

Kerry Park offers an extraordinary vista of the city skyline, Space Needle and all. On a clear day, Mount Rainier can be seen in the background. Photographers can often be found here as the sun goes down.

More from Washington state

Washington’s national parks and Seattle might be its most famous attractions, but you could see them all without even leaving the western half of the state — and even then, you would be missing other attractions in the west.

Mount St. Helens

In the southwest of Washington, visitors can find the Mount St. Helens National Volcanic Monument, just south of Mount Rainier. “And that’s a really cool place to go visit,” Coleman said, “Because you can actually drive right up into the blast zone.” The total devastation wrought by the volcano’s 1980 eruption contrasts with the new growth that has regenerated in the area, making for a thought-provoking trip to a natural wonder that could easily be overshadowed by Mount Rainier.

The Columbia River Gorge isn’t far away: “The Gorge is really a fantastic place. It’s basically along the Columbia River, which is the river that separates us from Oregon. That whole gorge region … both the Washington and Oregon sides, is kind of like waterfall central,” said Coleman.

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Whale watching

Orcas, gray whales and humpback whales can be spotted in Washington’s Puget Sound all year round, and whale-watching boat tours are available at multiple locations along the coast. Most boats won’t get too close to the whales, as some are endangered and have been killed in collisions with ships. Make sure to dress warmly and bring your binoculars.

Eastern Washington

The eastern portion of the state is totally different from what many think of as the wet environs of the Pacific Northwest. On the other side of the Cascade mountain range, it gets dry and hot. The city of Spokane provides an urban hub for excursions eastward and, though smaller than Seattle, offers arts and culture, craft beer and wine, and other trappings of an urban center.

South of Spokane lies Pullman, where Washington State University is located. Further south still is Hells Canyon, the deepest river gorge in North America. Though it lies mostly in Oregon and Idaho, a portion of it does fall in southeastern Washington. This gorge is popular for high-speed jet-boating during the hot summers.

The golden, rolling fields of wheat of Washington's Palouse region are seen beneath a blue sky with wind turbines in the background

Rolling wheat fields of Washington’s Palouse region are seen from Steptoe Butte. The Palouse region experiences short, warm, dry summers and cold, snowy, cloudy winters. The region is also home to Palouse Falls, the official state waterfall of Washington, located in Palouse Falls State Park. The falls cascade down 198 feet to the Snake River. (Bernard Friel/Education Images/Universal Images Group via Getty Images)

The warm, sunny weather makes the region great for agriculture. “Wine country” is in the center of the southern portion of the state. The region, as you might be able to guess, is known for its more than 300 vineyards and wineries.

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Road trips

There are many reasons to visit Washington state, but many visitors tend to fit within a certain profile, Coleman told Fox News Digital: “Everybody has their different thing that they’re wanting to accomplish when they visit, but overall … if they’ve chosen Washington as their destination, chances are they’re looking for outdoor recreation or, you know, scenic views, seafood or national parks.”

US NATIONAL PARK ATTENDANCE SOARED IN 2023 AS MILLIONS OF AMERICANS CONTINUE TO HEAD OUTDOORS

That is why Scenic Washington offers pre-planned road trip itineraries. The popular Cascade Loop begins from Seattle and circles the northern half of the state. The Palouse Scenic Byway explores Washington’s east, from its central desert lands to lakes and waterfalls to the rolling wheat fields of the Palouse region, which holds the largest concentration of wheat per acre in the world.

For more Lifestyle articles, visit www.foxnews.com/lifestyle.

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Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

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From Market Leadership to Technological Leadership: ANGEL Brand Strategy Upgraded Completely

SHENZHEN, China, April 19, 2024 /PRNewswire/ — On April 18th, ANGEL held its “Global Leading Water Purification Technology” strategic elevation and new Space Master Series product launch event at the Beijing Water Cube. In addition to unveiling its new strategic direction as a “leading global expert in water purification technology”, ANGEL also launched the ANGEL Space Master Series, a comprehensive line of whole-house water purification products. At the event, ANGEL’s water purification technology experience ambassadors shared their experiences with the new products, while strategic alliances were announced, allowing guests to engage in discussions about innovative achievements in water purification technology. This marked a new beginning for the water purification industry.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

A New Strategic Upgrade: From Market Leadership to Technological Leadership

Kong Na, Chairman and President of ANGEL Group, shared the evolution of the ANGEL brand and the water purification industry at the event. In her address, as a pioneer deeply engaged in water purification technology for 36 years, ANGEL experienced three significant technological advancements, guiding China’s water purification industry through three eras while adhering to technological innovation as its driving force.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

When ANGEL introduced the first water purifier in China in 1988, it ushered in a new era of pure drinking water. Subsequently, in 2019, the unveiling of the A7 large-capacity water purifier propelled the industry into the era of purifying water for washing purposes. Then, in 2022, the launch of the X-Tech series high-end whole-house water purification solution paved the way for a global leap forward in water purification. Over the past 36 years, ANGEL has continuously achieved technological breakthroughs, guiding the industry across three eras. To date, ANGEL has participated in the revision of 17 national and industry standards and accumulated over 900 patents. Furthermore, its research findings have been published five times in reputable SCI journals. Between 2022 and 2023, the company won 19 international invention awards, making significant advancements in the field of global water purification.

At the event, Kong Na announced that ANGEL is embarking on a comprehensive strategic upgrade, outlining the new strategic objective of becoming the “leading global expert in water purification technology.” With a global perspective, ANGEL intends to implement a “going global” strategy, disseminating its cutting-edge water purification technology to households worldwide, enabling more families to live a safe, healthy, and stylish lifestyle through purified drinking water.

At the same time, Kong Na unveiled ANGEL’s new brand identity, revitalizing the brand image with a more digital and international perspective. In addition to embodying ANGEL’s innovation and leadership in water purification, the new brand identity will also function as a conduit for ANGEL to foster emotional connections with consumers worldwide.

Finally, Kong Na announced the new global brand ambassador—Xiao Zhan. In the future, ANGEL will work hand in hand with Xiao Zhan to promote China’s water purification technology to global audiences, initiating a new era in global water purification efforts.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

World Record Certification for New Water Purification Products, Embarking on a New Era of Whole-house Water Purification

At the event, Zhao Kai, Vice President of ANGEL Group, officially launched the all-new ANGEL product—the Space Master Series whole-house water purifier. This innovative line features a new “ecological fusion” design language that combines technology with art. The series comprises the M7 Home 800 whole-house large capacity water purifier and the whole-house Mini softener, drawing inspiration from Mount Namcha Barwa, the purest mountain peak globally.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

Zhao Kai unveiled the M7 Home 800, equipped with the innovative Loong Whale Dual-effect Water Purification System. This system achieves a large flow rate of 4T/h due to the innovative Dual ACF2000 composite filter element, ensuring thorough water purification for the entire household. This patented reverse osmosis filter element 2.0 Plus has a purification capacity of 64,000 liters, maintaining optimal water quality for up to 8 years without degradation. This filter element has won the 2022 China Patent Excellence Award, as well as many other domestic and international awards such as the Golden Award at International Exhibition of Inventions of Geneva in 2022 and the Golden Award at Asia International Innovative Invention Exhibition in 2023. Furthermore, the product incorporates APCM aerospace antibacterial technology that has a 99.99% removal rate for ESKAPE super-resistant bacteria, ensuring the health and safety of users.

As a significant note, ANGEL accomplished the successful launch of APCM antibacterial material into space on December 17, 2023, with the test mission concluding triumphantly. At the event, Dr. Li Fei, the expert overseeing the space experiment payload, affirmed that the antibacterial material of APCM still exhibited strong bactericidal properties even when subjected to the challenging conditions of microgravity, high vacuum, and strong radiation. This material has great application prospects in medical care, food protection, and other fields.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

Subsequently, Zhao Kai gave a detailed introduction to the whole-house Mini water softener. With its dual-drive and enhanced softening system, the water flow path is increased by about 2.2 times, enabling dual softening capabilities. Additionally, the system employs a flat water distribution system to achieve a 360° full-coverage spray. It achieves a softening efficiency up to 99.8% and a flow rate up to 1.5 m3/h to meet dual toilet soft water needs. The product is also equipped with IoT intelligent interconnection, patented AI smart multi-way valve technology, real-time monitoring of machine status, and automatic customization of regeneration cycles, thus effectively reducing the volume of the softener.

Designed with exquisite quality, the Space Master Series has garnered the World Record Certification Agency’s “smallest volume whole-house water purification system” certification. According to Zhao Kai, the Space Master Series comprehends users’ challenges in whole-house water purification, addressing the needs of small and medium-sized households through miniaturization, and opens a new era in whole house water purification.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

Convergence of Forces to Build a New Industry Ecosystem

ANGEL continues to lead industry development through technological advancements. At this event, experts and professionals from different fields, along with strategic partners, were invited to inaugurate the Water Purification Technology Alliance. This alliance aims to foster cross-border innovation, dismantle barriers to innovation, and accelerate the upgrade of the water purification industry in China and around the world.

Among them, Zhuang Ziyu, founder of BUZZ (Büro Ziyu Zhuang) Architects, and Bilibili’s renowned science popularization content creator Bi Dao (Bi Xiaotian) were invited as ANGEL’s water purification technology experience ambassadors to share their insights. Zhuang Ziyu expressed that for home design, reducing product dimensions will yield more ample space for creativity. ANGEL’s innovations in products and technology provide crucial support for spatial construction. Moreover, Bi Dao believes, “Every technological breakthrough continuously enhances the efficiency and quality of water purification. With 36 years of technological innovation, ANGEL has consistently led industry development, step by step, using technology to turn impossibilities into possibilities and making possibilities more closely aligned with daily life.”

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

The event also included the ANGEL Strategic Alliance Launch Ceremony. With an inclusive approach, ANGEL is poised to collaborate with global partners to leverage their collective strengths and resources, aiming to enhance consumer experiences by offering more convenient and high-quality services. This endeavor will inject new momentum into the market in the future.

Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully
Spearheading the New Era of Water Purification: ANGEL Space Master Series New Product Launch Event Held Successfully

Starting from small things and aiming for big achievements, ANGEL has always adhered to its original mission, starting from the “trivial matter” of water purification. The company will continue to enhance its efforts in the field of water purification, guided by the strategic vision to be a “leading global expert in water purification technology”. Simultaneously, it is dedicated to promoting China’s water purification technology worldwide.

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Signs of multiple sclerosis can be detected in blood 5 years before symptoms appear, new study finds. Here’s why this breakthrough is important.

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A new study found that in about 10% cases of multiple sclerosis, the body begins producing a distinctive set of antibodies against its own proteins years before symptoms emerge. “Multiple sclerosis is a complex autoimmune disease that is difficult to diagnose,” Colin Zamecnik, a researcher at UC San Francisco and lead author on the paper, tells Yahoo Life. “We believe that a subset of patients that go on to develop MS, around 10%, develop antibodies against a common protein domain that is prevalent in humans and viruses that infect us.”

This patient population exhibits the antibodies many years before the onset of MS. Zamecnik says that when they are tested at the time of their first disease flare, the antibodies show up in both their blood and cerebrospinal fluid. “We believe it’s possible that these patients are exhibiting cross reactive response to a prior infection, which agrees with much current work in the literature around multiple sclerosis disease progression,” he says.

Scientists already know that B cells — the cells that make antibodies — are crucial for MS disease progression. Because of this, UCSF researchers believed that profiling the antibodies in people that have, or go on to develop, MS would give them insight into the disease and reveal a possible biomarker — a measurable sign they could look out for.

“From the largest cohort of blood samples on earth, we obtained blood samples from MS patients years before their symptoms began and profiled antibodies against self — autoantibodies — that are associated with multiple sclerosis diagnosis,” says Zamecnik. “We found the first molecular marker of MS that appears up to five years before diagnosis in their blood.”

Why this is important

Although the biomarker is associated with a subset of MS patients when tested at the time of their first flare or relapse, 100% of those people exhibiting the biomarker eventually developed MS. “This could be a useful tool to help triage and diagnose patients with otherwise nonspecific neurological symptoms and prioritize them for closer surveillance and possible treatment,” says Zamecnik.

Dr. Cole Harrington, a neurologist at the Ohio State University Wexner Center, agrees that the discoveries could help diagnose MS earlier, and lead to earlier treatment.

“We do know from data in Canada looking retrospectively at people in emergency room visits and visits to health care systems, that many people have a prodromal phase of MS where they have a lot of symptoms before they’re actually diagnosed and we don’t have good biomarkers or ways of identifying people who are at risk for MS or will go on to develop MS,” says Harrington. “I think any advancement in that area will be helpful for diagnosis because the symptoms early on tend to be somewhat nonspecific.”

The biomarker could also help a category of people who have radiologically isolated syndrome, which means they have white matter changes on the brain — an indication of MS — but don’t have any classical MS relapses.

“They don’t meet criteria for MS, but some of them are at risk for developing MS, so potentially utilizing these biomarkers within that patient population may be helpful to determine which of those people are going to go on to develop MS or [have an] increased risk of developing MS,” Harrington says.

Same may occur with people who had one clinical MS relapse but don’t meet the full criteria for MS, as well as people who have relatives with MS and also have white matter changes on their brain.

“Not everybody who has a first degree relative develops MS, but the risk is higher in those individuals and so potentially applying it to those people as well with a first- or second-degree relative could be helpful,” says Harrington.

Who is at risk for MS?

According to the National Multiple Sclerosis Society, most people are diagnosed with MS between the ages of 20 and 50. However, it can occur in younger people, too. While MS can affect anyone in any ethnic group, in the U.S., the condition most commonly occurs in white people of northern European descent. MS is not believed to be passed down to relatives. However, 200 genes have been identified to contribute in a minor way to a person’s overall risk of developing MS.

Research shows that the following factors contribute to developing MS:

What are the early signs of MS?

Common symptoms of MS include the following:

Early diagnosis of MS makes a big difference

Emerging data shows earlier treatment of MS with more effective therapies is better in terms of reducing disability long-term.

“If people are not diagnosed earlier in their symptoms or have a delayed diagnosis, we are missing out on that critical therapeutic window of time where we can make a difference by suppressing the inflammation and preventing new lesions from forming,” says Harrington.

Several ongoing trials are investigating the impact of using early aggressive therapy vs. an escalation approach, which involves starting treatment with lower efficacy therapy, and moving onto more aggressive therapy when the person has a relapse or new lesion.

“I think this field is changing in terms of [scientists’] thinking and that early, more aggressive treatment is beneficial long-term for people with MS in terms of their prognosis and outcome,” Harrington says.

The best way to do this, according to Zamecnik, may be a simple antibody test that is highly specific for MS. “This signature will be the focus of future work investigating how the immune system recognizes cross talk between pathogens and self in the context of autoimmune disease,” he says.

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Choosing a New Dentist…

Take your time choosing a dentist and don’t wait for an emergency dental problem to find one! Our blogging team have identified below several things to consider when selecting one.

Location and office hours

Choose a dentist close to your home or place of work. This will make it easier to schedule visits, avoid the stress of traffic congestion and ensures you arrive on time. Also, make sure that the dental office is open on the days and at the times when you are able to schedule an appointment.

Cost

Does the dentist accept your medical insurance cover? Does the dentist offer multiple payment options (credit cards, personal checks, payment plans)? If your insurance plan requires referrals to specialists, can this dentist provide them?

Also, given that costs vary from practice to practice. Get estimates of what your dentist might charge for common procedures such as fillings, crowns or root canal work to be done. Even though you may have dental insurance, you may be paying required to pay part of the costs yourself above certain levels.

It’s important to note that it’s worth it to pay a little extra to find a dentist who will give you excellent care in an event which you feel comfortable.

Personal comfort

One of the most important things to consider when you choose a dentist is whether you feel comfortable with that person. Do you feel comfortable enough to be able to explain symptoms and ask questions without feeling awkward or like you are imposing on their time? Do you feel like the dentist hears and understands your concerns? Would you feel comfortable asking for pain medicine, expressing your fear or anxiety, or asking in depth questions about a procedure?

Professional Qualifications

The dentist’s reception should be able to tell you about the dentist’s training, registration details and qualifications. The office also should have policies available to you on infection control. If the staff seems uncomfortable answering these questions, or you are uncomfortable with their answers, consider finding another practice. You can also obtain information about a dentist’s qualifications from the local dental association and Government Licensing Board who oversee the licensing of dentists.

Emergency Care

Find out what happens if you have an emergency, either during normal office hours, at night or on a weekend. A dentist should not refer you to a hospital emergency room. You should be able to contact your dentist or be referred to a suitable alternative dentist at any time by calling their reception during or after work hours.

How To Find a Dentist


Here are some suggestions on finding dentists to evaluate:

People to ask:

  • Your friends and family— Friends and family members are a great resource to learn about a trusted dentist. They can tell you about the personality of the dentist and office staff, and answer your questions. Here are some good questions to ask:
    • How well does the dentist explain treatment options?
    • Was he or she kind, gentle and understanding?
    • How long do you have to sit in the waiting room?
    • Do you feel comfortable asking questions?
    • How does the office handle emergencies?
    • How long do you have to wait for an appointment?
    • How are bills handled?
  • Your Current Dentist— If you are moving, ask your current dentist if he or she knows of someone to recommend near your new home.
  • Your Current Doctor— Your physician may be able to provide some names of dentists.
  • Local Dentist Reviews — If you are wanting a specific procedure, check Google reviews of dentists operating in your area that do that work for insights into past client thoughts on their experience. Then check their website to investigate the dentists philosophy.

Places to call:

  • Your dental insurance company— Your insurer will provide names and contact information for dentists in your area who are approved providers of dental services. Usually you will pay a lower fee if you use these dentists under your policy. Your insurer also may have other information, such as whether the dentist accepts new patients, does veneer work, implants etc.
  • Your Local Hospital– Some hospitals have their own dental clinics, or can recommend local dentists.
  • Your Local Dental Association —A dental association can provide names of dentists who are current and members of good standing.

Besides all of the above  possibilities to locate a suitable dentist to call, you can also check the yellow pages, do a Google search for local dentists, check business directory listings and dentists on social media.

Several of the blogging team have had great personal experience with Smile Concepts, and recommend to our readers this leading Sydney full service dentist located in the heart of Sydney’s CBD.

At the heart of Smile Concepts is their philosophy on a total commitment to excellence in dental care & service. They are dedicated to designing beautiful smiles in a caring & premium environment.

Learn more about Smile Concepts and their range of dental services here: https://www.smileconcepts.com.au/

Why Select Polished Concrete Floors?

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Polished concrete is a hard wearing floor. It’s easy to maintain, easy to clean, and it’s stylish. That’s why so many interior designers, architects as well as home and business owners choose polished concrete flooring for their residential, commercial, or industrial projects.

It’s resistant to industrial chemicals, oils, food stains, greases, and fatty materials, so it’s very easy to clean. Thanks also to its reflective quality, it bounces light around a room, making the ambience appear lighter and brighter.

Specialist contractors mechanically grind the floor, polish and seal the concrete, or add a range of gloss finishes if that is desired. They can suggest the most cost-effective finish for the purpose of the project.

BENEFITS OF POLISHED CONCRETE FLOORS

Our research found a large number of benefits of concrete floors including these:

  • By utilising the concrete floor slab as your finished floor, the environmental costs associated with the manufacture of other floor coverings, adhesives and all installation materials are eliminated. An eco-friendly solution that a lot of property owners are looking for to meet ‘green building’ ratings.
  • The random variety of stones in the polished concrete makes each floor unique and very low maintenance.
  • Polished floors are easy to clean and when finished look great. The floor’s sealer repels spillages & stains and easily cleaned up.
  • These floors do not harbour dust mites as carpet does, so a hypo-allergenic surface for home and business owners.
  • Polished concrete does not give off volatile organic compounds, (VOC’s) which can be found in composite timber flooring and coatings such as epoxies. 
  • We all know that concrete floors are long lasting, durable and outlast any other flooring alternative.
  • There is a cost for polishing and sealing the floor, but over time it becomes more cost effective than vinyl, timber, carpet, and tiles which eventually will need replacing.

The blogging team has had great experience in getting polished concrete floors done by AMP Polishing, a Sydney based floor polishing expert with over 25 years of experience in the industry.

They have all the experience for the best polished floor solution for your home or business. Their team assist get the perfect polish floor option to match home and business owners expectations and budget. They have polished thousands of concrete floors across Sydney, guaranteeing that you’ll receive an outstanding finish to the interior of your project. Their dedication to quality and customer service is supported by their extensive list of customer testimonies and work examples the highest quality polished concrete in the industry.

Projects they work on range in size, and offer a different finishes and styles to suit any space. Their services are offered on new builds and recent pours, as well as existing concrete floors and renovations. Clients get great value for money with options for all styles and budgets.

Polished concrete not only adds elegance to any floor but also ensures durability at an affordable cost anywhere across all locations in Sydney and across New South Wales. They provide the mechanically polished concrete finish, to the highest standard suitable for epoxy coatings for all project locations.

For more information on polished concrete surfaces or epoxy coatings for both residential and commercial projects, view AMP Polishing’s website here: https://www.amppolishing.com.au

Explore Virginia: What to do, tour and see on your next vacation

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Virginia’s motto, “Virginia is for lovers,” captures only a fraction of its allure.

The state boasts a wide range of activities that cater to solo travelers, groups of friends and families alike.

Virginia has historical treasures like Colonial Williamsburg, Thomas Jefferson’s Monticello and George Washington’s Mount Vernon. 

THE BEST TOURISM SPOTS IN TEXAS FOR THE WHOLE FAMILY

The state’s landscapes and family-friendly theme parks offer ample entertainment for those looking for fun and outdoor adventures.

Here’s much more. 

Virginia is for Lovers sign

“Virginia is for Lovers” has been the slogan of Virginia since 1969. (Joe Sohm/Visions of America/Universal Images Group)

Historical sites in Virginia for an educational trip

Virginia offers a view into America’s past; visitors can journey through the nation’s historical narrative. The state encapsulates a significant part of Civil War history because the Confederacy moved its capital to Richmond, and the state witnessed more battles than any other. 

This rich historical landscape of Virginia offers abundant learning experiences for families and history buffs.

Among the notable destinations is the district of Jackson Ward in Richmond, once heralded as the “Harlem of the South” and celebrated as a cradle of Black entrepreneurship. It stands as a monument to African American communities’ vital contributions and vibrant culture.

TENNESSEE TRAVEL GUIDE: WHAT TO SEE AND DO IN NASHVILLE AND THROUGHOUT THE STATE

Colonial Williamsburg is an immersive experience that allows visitors to travel back to the Colonial era. The historic park includes a living rendition of this period as actors re-enact Colonial life on a 301-acre backdrop of reconstructed shops, homes and other structures modeled after their original forms. 

Soldier walks at Arlington National Cemetery

The changing of the guard is a ceremony held at the Tomb of the Unknown Soldier at Arlington National Cemetery. (Kevin Carter)

Arlington National Cemetery

Arlington National Cemetery, renowned as a final resting place for many of the nation’s esteemed heroes, is the most famous cemetery in the world. Hosting more than 300,000 veterans who served in American conflicts spanning from the Revolutionary War to recent engagements in Iraq and Afghanistan, the cemetery has been a solemn sanctuary since 1864. 

It allows visitors to pay respect to the sacrifices of the United States’ servicemen and women.

The cemetery has been a solemn sanctuary since 1864. 

Arlington National Cemetery is accessible every day of the year without charge and welcomes guests to tour the grounds. The changing of the guard ceremony at the Tomb of the Unknown Soldier, occurring hourly from October to March and at 30-minute intervals from April to September, is an intricate observance many enjoy.

The grave of President John F. Kennedy stands among a host of other significant tombs available to visit.

Sites such as Historic Jamestowne

Virginia houses many prominent American landmarks, including Historic Jamestowne, which was recognized as North America’s initial permanent English settlement. Sent by the Virginia Company, explorers reached Virginia’s shores in quest of precious metals and to found an English colony in the New World.

BECOME AN INTERNATIONAL TRAVELER ON A BUDGET BY VISITING THESE 13 AFFORDABLE DESTINATIONS AROUND THE WORLD

A visit to this historic island typically lasts several hours to half a day, during which guests can explore the various historical landmarks. Historic Jamestowne offers a range of educational activities that family members of all ages can enjoy.

Theme parks and water parks in Virginia

Virginia offers much more than historical monuments. Virginia’s thrilling theme parks, including Massanutten WaterPark, Ocean Breeze Waterpark and Water Country USA, offer an array of adventures for travelers seeking fun and excitement.

Kings Dominion

Families, friends and lovers can experience world-class rides at Kings Dominion, a 400-acre combination theme and water park. The park features over 60 rides and attractions, boasting some of the largest on the East Coast. Admission includes access to Soak City, the park’s expansive 20-acre waterpark.

Kings Dominion Amusement and Water Park in Virginia on a clear day with clouds in the sky

Virginia is home to numerous theme and water parks, including Kings Dominion. Visitors can also enjoy the sister water park, Soak City, which is included in the admission price. (Linda Davidson/Washington Post)

Busch Gardens

Busch Gardens, acclaimed by visitors as the world’s most beautiful theme park, indulges visitors with a European-themed experience. As guests travel through the park, they witness the cultural highlights of England, Scotland, Ireland, France, Germany and Italy through cuisine, roller coasters, live shows and other attractions.

Great Wolf Lodge

The Great Wolf Lodge in Williamsburg spans 55,000 square feet and is a premier indoor and outdoor family fun attraction. It features a lazy river, a children’s pool, and tube slides suitable for the young and the young at heart.

Outdoor activities

Virginia is a mecca for those who enjoy living life outdoors. From hiking in Shenandoah National Park to exploring the Grand Caverns, the state has an outdoor adventure for everyone. 

MAKING CAMPING FUN FOR EVERYONE WITH S’MORES, GAMES AND MORE

Kayaking on the Potomac River

Adventurers of all ages will enjoy traveling down the Potomac River, which George Washington called the “Great Avenue into the Western Country.” With more than 300 miles designated as a National Recreation Trail, many sections exist for day or weekend trips. The Potomac River connects four states and the District of Columbia. 

View of Potomac River on a clear day

The Potomac River is around 405 miles long, making it the fourth-largest river along the Atlantic coast.

Shenandoah National Park 

Shenandoah, the first of Virginia’s national parks, offers visitors sights of all varieties. With cascading waterfalls, scenic vistas and majestic fields of wildflowers, the nature enthusiast will have no unsatiated appetite for exploration. 

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Shenandoah National Park offers hikes for all levels, starting at 2.5 miles. Visitors can take advantage of these walking paths and hiking trails to see all that the Shenandoah Valley has to offer.

The Natural Bridge

One sight that can’t be missed is Natural Bridge State Park, located in the Shenandoah Valley. The Natural Bridge is a natural geological formation that has been designated as a National Historic Landmark and Virginia Historic Landmark. Visitors can traverse under the bridge and then travel down 34 stories to explore the deepest caves on the East Coast.

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The Grand Caverns

Discovered in 1804 by Bernard Weyer, the Grand Caverns are the United States’ oldest show cave in continuous operation, as stated on the park’s official website. 

Visitors can explore rock formations, Civil War-era treasures and above-ground adventures like a fitness trail and miniature golf course. 

For more Lifestyle articles, visit www.foxnews.com/lifestyle.

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Paris Baguette Teams Up with Paris Saint-Germain to Broadcast its “Let’s Paris” Ad Around the World

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What are the Top-Picks of Paris Saint-Germain Players at Paris Baguette?

  • Paris Baguette releases first global Digital ad in South Korea, the United States, France, and Southeast Asia
  • Paris Saint-Germain players star in Mukbang video, captivating audiences with a humorous twist in Paris Baguette’s latest ad; Five products selected by players, now available at Paris Baguette

PARIS and SEOUL, South Korea, April 19, 2024 /PRNewswire/ — Paris Baguette has released its “Let’s Paris” ad video, in collaboration with Paris Saint-Germain, the most successful football club in France, to both Korean and global audiences.

Paris Baguette’s “Let's Paris” ad video, in collaboration with Paris Saint-Germain
Paris Baguette’s “Let’s Paris” ad video, in collaboration with Paris Saint-Germain

The Let’s Paris video is themed around the favorite picks of Paris Saint-Germain’s star players. The players featured in this video happily enjoy the flavors of Paris Baguette’s newest breads, adding an extra spark to their tasting adventure.

The video opens with players savoring Paris Baguette treats at Parc Des Princes, the home stadium of Paris Saint-Germain. While the players initially gathered to celebrate a teammate’s birthday, they were so captivatedby the delicious breads that they forgot the celebration.

The five signature products from the ad will soon be available at Paris Baguette stores. The “Chaltteok Cream Bread,” paired with Lee Kang-in, blends the chewy nature of Chaltteock (Glutinous rice cake), inspired by Gyeongdan (Sweet rice balls), with the airy sweetness of whipped cream, symbolizing the cultural rendezvous between Korea and France. The “Strawberry Tart,” a dessert shaped like a crown of victory and adorn with fresh strawberries and a rich vanilla bean custard cream, is reminiscent of goalkeeper Gianluigi Donnarumma. The “Vanilla Flan Tart” represents Nuno Mendes, a delightful reinterpretation of Paris Baguette’s popular French dessert, merging the essence of flan into a tart to signify defense with its sweet allure. The “Kouign-Amann,” a traditional French pastry known for being crispy on the outside and moist inside, is a perfect match for the forward Ousmane Dembélé. Lastly, the “Onion Croque Monsieur,” a classic French hot sandwich that brings together the delicious contrasts of sweet and savory with its mix of onions, ham, cheese, and béchamel sauce, impeccably mirrors Marco Asensio’s versatile skills in both offensive and defensive gameplay.

YeonJeong Kim, VP of Marketing at Paris Baguette stated, “This ad, as part of our global partnership with Paris Saint-Germain, is sure to bring joy to customers and fans worldwide.” She further noted that “It holds significance in unfolding our global marketing strategy as the ad is released to reach global audiences across South Korea, the United States, France, and Southeast Asia for the first time”.


LET’S PARIS! ParisBaguette X ParisSaintGermain!

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China’s Yiwu Establishes Welcoming Committee to Attract International Buyers

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YIWU, China, April 19, 2024 /PRNewswire/ — On April 16th, the Yiwu China Commodities City unveiled a new welcoming committee, comprising the region’s top women entrepreneurs, to aid international buyers in sourcing local products. Over 120 skilled businesswomen from the committee will provide tailored one-on-one services, demonstrating the market’s commitment to exceptional customer care.

Yiwu, known for over four decades as a hub of commerce, continues to attract a global clientele, establishing itself as a significant resource for goods and wealth generation. The market’s annual 415 Global Wealth Creation Season features extensive purchasing incentives for buyers. The formation of this high-profile group of female entrepreneurs is a notable effort to elevate service standards during this bustling period.

During this year’s 415 Wealth Creation Season, the Yiwu market is highlighting 20 categories of its most current, trending, and best-selling products, including accessories, bags, cultural items, daily necessities, bedding, and clothing. The market has organized multiple trade-facilitation events including trade exhibitions, new product debuts, and procurement negotiation sessions. Additionally, the offerings are concurrently featured in online joint exhibitions on the Chinagoods platform (chinagoods.com), streamlining the purchasing process for business buyers.

As digital trade and AI-enhanced e-commerce continue to reshape global commerce, Yiwu’s merchants are moving beyond traditional business models, which relied heavily on face-to-face interactions, physical exhibitions, and passive online inquiries. They have started to proactively court customers through advanced digital tools, offering a comprehensive one-stop “VVIP” service.

During and following this year’s 415, the welcoming committee, as the newly formed group, plans to take it step further, by fully exploiting online platforms, including leading multi-country social media channels, independent brand websites, and the Chinagoods platform, to tap into current global purchasing trends. They are committed to engaging in real-time, highly targeted interactions with buyers worldwide to ensure timely and effective service. Furthermore, the group of businesswomen are set to enhance their international presence through online videos, live streaming, and other digital communication methods, directly accessing global markets.

The Yiwu market, known globally as the preeminent wholesale market for small commodities, has amassed a comprehensive array of supply chain resources worldwide. Over four decades, it has cultivated an expansive global sourcing network, operating under the “buy globally, sell globally” ethos. The institution of the 415 Wealth Creation Season and this new cadre of entrepreneurial women are critical measures in enhancing the market’s international standing and providing a unique buying experience for global purchasers.

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SK chemicals, Dongsung Chemical, and Black Yak Collaborate on Commercializing Sustainable Footwear

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  • Revolutionizes cushioning with high-elasticity biomass-based materials
  • Unified domestic industries go beyond performance to promote sustainability in the outdoor industry

SEONGNAM, South Korea, April 19, 2024 /PRNewswire/ — SK chemicals (CEO Ahn Jae-hyun), Dongsung Chemical (Co-CEOs Baek Jin-woo and Lee Man-woo), and BYN Black Yak (Chairman Kang Tae-sun, hereinafter Black Yak) announced on the 18th that they’ve developed sustainable footwear materials using the naturally-derived material “ECOTRION” and applied them to Black Yak’s “Trekking Shoes 343 MAX.”

Trekking shoes commercialized by SK chemicals, Dongsung Chemical, and Black Yak
Trekking shoes commercialized by SK chemicals, Dongsung Chemical, and Black Yak

Consumers are attracted to the trekking shoes, launched as a new product this spring, because they satisfy both the high functionality required for outdoor activities and the value consumption trend for eco-friendly materials that reduce greenhouse gases.

The three companies introduced this product after a year of collaboration. SK chemicals is the supplier of 100% bio-based polyol “ECOTRION,” while Dongsung Chemical develops the bio-polyurethane resin “NEOPAN®” for footwear using this as a raw material. Utilizing this material, Black Yak produced the “Foot Pillow Cushioning Foam,” which is applied to the heel support layer of the midsole to minimize loading on the ankle and knee joints.

The midsole of trekking shoes is a key component that determines the footwear’s weight and acts like a car’s suspension to provide the level of function. Cushioning is important because the midsole must absorb the impact on the body and ensure safe strides, even on rough terrain.

Dongsung Chemical’s bio-polyurethane resin “NEOPAN” for footwear maintains the high elasticity and flexibility of existing polyurethane resins while using bio-based raw materials, providing the shock absorption function of the “Foot Pillow Cushioning Foam.”

ECOTRION, utilized in NEOPAN, is an eco-friendly material that uses raw materials that reduce greenhouse gas emissions by approximately 40% in comparison to conventional petrochemical raw materials. It is utilized in the production of spandex, artificial leather, and urethane elastic materials that are challenging to recycle. ECOTRION has one less carbon atom in its chemical structure compared to petrochemical materials, which gives it a helical-shaped polymer structure that enables the production of products with high elastic resilience, similar to a spring.

Kim Eung-soo, Head of SK chemicals’ Green Materials Business Division, stated, “Bio-materials, along with recycled plastics, are one of the promising alternatives to replace petrochemical materials. We plan to actively highlight the sustainability and functionality of PO3G, focusing on big brands that are leading the sustainable trend with bio-materials.”

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