Thursday, June 11, 2026
Google search engine
Home Blog Page 12

VINEXPO ASIA 2026: THE PRESS KIT IS NOW AVAILABLE (VOL. 2)

0

HONG KONG, May 22, 2026 /PRNewswire/ — Vinexposium is giving its 2026 Hong Kong event a whole new dimension. Vinexpo Asia is growing, restructuring and evolving to align with new consumption trends. Three spaces – Vinexpo Asia, Be Spirits and Be No – will be hosted under the same roof to embrace the ever-expanding range of alcoholic and no-alcohol drinks.

Press Kit Vinexpo Asia 2026
Press Kit Vinexpo Asia 2026

In this volume, you will find all the essential information about this edition:

  • Key figures and event highlights.
  • Major 2026 trends shaping the W&S industry in Asia.
  • Markets overview.
  • Practical information to attend and cover the show.

ACCESS THE PRESS KIT HERE

For more information, visit the Vinexpo Asia, Be Spirits and Be No websites
View photos from the previous edition in Hong Kong here 

Source

Pinkfong’s “Baby Shark” Swims Into Spotify’s Billions Club

0
  • Surpasses 1 billion streams on Spotify, marking a rare milestone for a character-driven global hit
  • Averages around 400,000 daily Spotify streams worldwide, or nearly five plays every second

Download images here

SEOUL, South Korea, May 22, 2026 /PRNewswire/ — The Pinkfong Company, the global entertainment company behind Baby Shark, today announced that “Baby Shark” has surpassed 1 billion streams on Spotify, joining the platform’s Billions Club and marking a major streaming milestone for the globally beloved song.

Baby Shark Spotify Billions Club
Baby Shark Spotify Billions Club

Spotify’s Billions Club recognizes songs that have surpassed 1 billion streams on the platform, a milestone reached by tracks from some of the world’s biggest recording artists. For “Baby Shark,” the achievement stands out as a rare milestone for a character-driven global hit, underscoring the strength of Baby Shark as a global content franchise with lasting cultural relevance across markets, platforms and generations.

Over the past 12 months, “Baby Shark” generated 137 million streams, reached 23 million listeners and was added to playlists more than 1 million times on Spotify. On average, the song is streamed around 400,000 times per day worldwide, or nearly five times every second. The track’s latest listening data also reflects its broad global appeal, with top markets spanning North America, Europe, Latin America, Asia and Oceania, led by the U.S., the U.K., Australia and Canada.

“Baby Shark has grown from a viral sensation into a global cultural touchpoint, connecting with audiences across languages, markets and generations,” said Minseok Kim, CEO of The Pinkfong Company. “Reaching 1 billion streams on Spotify is a meaningful milestone that reflects the song’s lasting appeal and continued global listenership. We look forward to expanding Baby Shark through music, stories and experiences that bring joy to fans around the world.”

“Baby Shark hitting 1 billion streams on Spotify is another landmark milestone for this magical song,” said Shabs Jobanputra, Founder of Relentless Records. “We are very proud to be in partnership with Pinkfong and celebrate this moment.”

First released in 2015, “Baby Shark” became a global phenomenon with its catchy melody, playful choreography and universal family appeal. The song has since built a record-breaking legacy across platforms, becoming the most-viewed video in YouTube history with more than 16 billion views, charting for 20 weeks on the Billboard Hot 100, and earning RIAA Diamond certification (11x Platinum) and BRIT Certified 5x Platinum. Baby Shark has also expanded into a global franchise spanning animated series, films, consumer products, live shows, and digital experiences.

About The Pinkfong Company

The Pinkfong Company is a global entertainment company that delivers content and entertaining experiences around the world. Driven by award-winning brands and IPs, the company has created and distributed a range of content across genres and formats including original animated series, world live tours, interactive games, and more. Believing in the power of entertaining and engaging content, The Pinkfong Company is committed to connecting people around the world and bringing joy and inspiration to worldwide audiences of all ages. For more information, please visit the website or follow the company on LinkedIn.

*Sony Music Entertainment UK’s Relentless Records are Pinkfong’s global music partner, alongside The Orchard who distribute the catalogue worldwide.

About Relentless Records

Relentless Records is one of the frontline labels at Sony Music Entertainment UK. Sony Music Entertainment is a global recorded music company with a current roster that includes a broad array of both local artists and international superstars. The company boasts a vast catalogue that comprises some of the most important recordings in history. Sony Music Entertainment is a wholly owned subsidiary of Sony Corporation of America.

About The Orchard:

The Orchard is a full-service music distribution company operating in more than 50 cities worldwide. The Orchard’s comprehensive artist & label services offering harnesses innovative technology, transparent data analysis, and expertise to reach fans and grow audiences. Offerings include digital and physical sales and marketing, advertising, brand partnerships, rights management, video monetization, collaborator splits and royalty accounting, publishing administration, neighboring rights, and more. Championed by an exceptional community of music lovers and experts, The Orchard empowers creators and entrepreneurs to grow and adapt in the dynamic, global industry. For further information, visit www.theorchard.com.

Media Contact

Hailey Kim

Communications Manager

The Pinkfong Company

hailey@pinkfong.com

Source

Experts stunned after uncovering Homer’s ‘Iliad’ on Egyptian mummy in unprecedented find

0

NEWYou can now listen to Fox News articles!

Archaeologists were stunned after recently discovering one of the greatest works of Western literature placed on top of a mummy in Egypt.

The one-of-a-kind discovery was announced by the University of Barcelona in an April 20 news release.

Researchers from the school uncovered a fragment of Homer’s “Iliad” while excavating a Roman-era tomb in the Egyptian town of Al Bahnasa.

ARCHAEOLOGISTS UNCOVER MULTISTORY BUILDINGS IN ONCE-THRIVING CITY LOST TO TIME

The tomb is located in the Al Bahnasa necropolis, once part of ancient Oxyrhynchus, which school officials said was “one of the most important cities of Greco-Roman Egypt.”

The University of Barcelona’s Oxyrhynchus Archaeological Mission has excavated the necropolis since 1992. The Roman-era tomb and mummy date back roughly 1,600 years.

Split image of Homer portrait, fragment of papyrus found atop mummy

Archaeologists in Egypt uncovered a rare fragment of Homer’s “Iliad” placed atop a Roman-era mummy during excavations at Al Bahnasa. (Universal History Archive/Universal Images Group via Getty Images; University of Barcelona)

The “Iliad,” an epic poem that centers around the Trojan War, is believed to have been composed around the 8th century B.C., more than a millennium before the mummy was buried.

Led by University of Barcelona professor Núria Castellano, excavators found that the papyrus was “placed on the abdomen [of the mummy] as part of the embalming ritual,” the school said in a statement.

CLICK HERE TO SIGN UP FOR OUR LIFESTYLE NEWSLETTER

“In previous campaigns, the Oxyrhynchus Archaeological Mission had already documented papyri written in Greek in similar positions, but all contained magical or ritualistic content,” the release noted.

A literary text such as the ‘Iliad’ had never before been found in this context.”

Depiction of Troy burning, people running away

Experts said the fragment comes from Book II of the “Iliad” and references Greek forces preparing for the Trojan War. (Fine Art Images/Heritage Images/Getty Images)

The fragment comes from Book II of the “Iliad” and describes the Greek forces preparing for the Trojan War. The text was identified by papyrologist Leah Mascia.

Ignasi-Xavier Adiego, a professor at the University of Barcelona, emphasized that previously found papyri had “mainly magical” content.

CLICK HERE FOR MORE LIFESTYLE STORIES

“Since the late 19th century, a huge number of papyri have been discovered at Oxyrhynchus, including Greek literary texts of great importance,” he said.

“But the real novelty is finding a literary papyrus in a funerary context.”

“[I]t is the first time in the history of archaeology that a Greek literary text has been found deliberately incorporated into the mummification process.”

During the excavation, archaeologists also uncovered Roman-era mummies and decorated wooden sarcophagi inside three limestone burial chambers, with the school noting damage from past looting.

But officials said the Homer fragment was the most notable — and they emphasized its rarity.

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

“The discovery is exceptional: It is the first time in the history of archaeology that a Greek literary text has been found deliberately incorporated into the mummification process,” the school noted.

Fox News Digital reached out to Adiego and Mascia for additional comment.

17th century depiction of Troy burning

The discovered papyrus contains lines from the Iliad, the classic Greek epic chronicling the siege of Troy. (Fine Art Images/Heritage Images/Getty Images)

The discovery follows a string of major archaeological finds in Egypt in recent months.

Last month, officials announced the discovery of a massive statue believed to depict the powerful pharaoh often linked to Exodus.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

Earlier this spring, archaeologists also announced the discovery of eight Egyptian papyrus scrolls alongside a cache of colorful coffins dating back more than 2,600 years.

Source

Essendon captain Andy McGrath sent to hospital as four go down in first-half Dreamtime at the ‘G carnage

0

Essendon captain Andy McGrath has been sent to hospital as the injury curse shadows the Bombers for another year.

After a disastrous 2025 season in the medical room, the Bombers are once again in damage control with another three injuries before half-time of their Dreamtime at the ‘G clash with Richmond on Friday night.

WATCH THE VIDEO ABOVE: Andy McGrath cops knock to the jaw

Know the news with the 7NEWS app: Download today Arrow

McGrath was had blood pouring from his mouth in the rooms after suffering a suspected broken jaw during the second quarter.

The skipper copped a stray but accidental elbow from Richmond forward Jonty Faull during a contest on the wing and came straight off the ground clutching at his jaw.

Essendon doctors monitored the defender during the second quarter and half-time before eventually making the call to send him to hospital.

Andy McGrath copped an elbow from Jonty Faull.
Andy McGrath copped an elbow from Jonty Faull. Credit: Channel 7
Andy McGrath was sent to hospital with a suspected broken jaw.
Andy McGrath was sent to hospital with a suspected broken jaw. Credit: Channel 7

Meantime, Matt Guelfi knew within about a minute of coming off the ground in the first quarter that he had reinjured his troublesome hamstring.

Medical staff didn’t even need to test the Bombers forward to work out he had suffered the damage, in what was his first game back from injury since Round 4, and only second for the year.

Guelfi let out an audible scream on the bench, not in pain, but frustration, with the out-of-contract 28-year-old having suffered hamstring setbacks in 2023 and 2025.

Matt Guelfi couldn’t believe his luck after going down with another hamstring injury.
Matt Guelfi couldn’t believe his luck after going down with another hamstring injury. Credit: Channel 7

Not long after Guelfi was ruled out, Essendon midfielder Sam Durham copped a knee to the head from Tigers forward Tom Lynch.

Durham initially tried to brush off doctors before eventually coming to the bench where he failed a head injury assessment.

He will now enter the AFL’s concussion protocols and miss at least the next 12 days.

Richmond, in the midst of an injury crisis of their own, also lost a player to concussion, with Jonty Faull going down in a brutal contest with Mason Redman.

Redman was in the motion of collecting the ball and will have no case to answer, but nonetheless collided with Faull, who was soon ruled out with concussion.

“For two teams that have copped some of the most brutal injury lists in the history of the game over the last two years, it simply is not stopping,” Xander McGuire said at half-time.

Faull will be the 17th player on Richmond’s shambolic injury list, which has derailed their season.

Source

Anamana Declares Era of ‘Billionaire Werewolves’ is Ending; AI-Native Strategy Sets Sights on Expanding $5B Micro-Serial Market into New Genres

0

Following heavy debate at the Los Angeles Vertical Drama Market, the AI-native pioneer scales its $2M incubator to empower creators producing social thrillers, sports dramas, and fantasy adventures at 3% of legacy production costs

LOS ANGELES, May 22, 2026 /PRNewswire/ — Returning from the frontline of the Los Angeles Vertical Drama Market (LAVDM), Anamana, the world’s first integrated creator ecosystem for AI-native micro-serials, today issued an industry-wide challenge to the ROI-driven incumbents dominating the $5 billion global short-drama market outside of China. 

While Chinese-led market titans like DramaBox used the four-day event to double down on highly profitable, formulaic “romantasy” tropes , Anamana is scaling its Anamana 100 Creator Incubator to prove that vertical, 9:16 mobile storytelling can successfully hold expansive narratives that captivate broader, diversified audiences. Backed by its proprietary agentic AI production platform, Anamana Studio, the company enables independent creators to bypass traditional cost bottlenecks — reducing production barriers by 97% and providing the economic freedom to take narrative risks.

According to Kai Pan, the Anamana executive who represented the company at LAVDM, the prevailing wisdom at the industry event was that micro-dramas are forever bound to pulp-romance playbooks. Anamana publicly rejects this limitation, pointing to a creative ceiling hit by traditional content factories that rely heavily on translating or “reskinning” identical scripts.

This commitment to creative diversification is reflected across Anamana’s global cohort, where creators are actively pushing past conventional genre boundaries: 

In Tokyo, Japan, director Masashi Kawamata is developing I am AI, a social media thriller tracking an influencer whose identity is weaponized against her via deepfake technology. 

“Micro-dramas today are built around very specific emotional transactions that have become commodified and safe,” said Masashi Kawamata. “The industry relies on billionaire CEOs and revenge marriages because they are emotionally efficient. The ceiling for this medium is much higher than what most platforms are willing to test, and Anamana understands that recognition and honesty create viewer loyalty in a way that cheap wish-fulfillment cannot.” 

In Bristol, UK, screenwriter Aishwarya Shah is producing Thin Ice, a high-stakes sports drama within a story about corruption, property redevelopment and family pressure.

“I think a lot of platforms would’ve wanted my concept flattened into a much safer, more straightforward romance very quickly,” added Aishwarya Shah. “But Anamana is committed to treating their audiences as intelligent and recognizes the hunger for stronger stories in more compelling worlds, while maintaining the pace and drama of the format.” 

In Berlin, Germany, filmmakers Markus and Tanja Laukkanen are directing Epic Quest Saga, a whimsical fantasy adventure inspired by Nordic mythology and folklore.

“Instead of making the story safer or smaller, Anamana pushed us to make it stranger, faster-paced, funnier, and more entertaining,” shared the Laukkanens. “That creative freedom is rare, especially in a market that can become overly focused on repeating existing formulas, and has been incredibly refreshing for us as filmmakers!”

On a smartphone, an audience is always a single “muscle twitch” away from abandoning content for a push notification or a social feed. While incumbents fight this distraction with endless melodramatic tropes , Anamana’s platform relies on high-resonance, diverse storytelling to drive audience retention. 

Anamana is currently deploying its initial $2 million Anamana 100 Creator Incubator fund to greenlight non-traditional genre projects from creators across five continents. Commercial availability of the Anamana Studio production platform for non-incubated creators is expected in 2026 Q3.

About Anamana

Founded in 2025, Anamana is an integrated AI-native micro-serial platform, production platform, and global creator ecosystem incubator. Human storytellers use the agentic AI Anamana Studio production platform to produce high-fidelity serialized video content with up to 97% lower capital, time, and manpower costs, lowering barriers to creation and increasing accessibility to individual creators. Micro-serials produced are then distributed to the market on Anamana’s own standalone app or third-party video services including YouTube or TikTok.  

Source

Airlines are struggling but China’s ‘Big Three’ face a tougher year than most

0

ZHENGZHOU, CHINA – MAY 16: China Southern Airlines aircraft are seen parked at Zhengzhou Xinzheng International Airport on May 16, 2026, in Zhengzhou, Henan Province, China.

Cheng Xin | Getty Images News | Getty Images

China’s biggest airline stocks have suffered more than others since the war in Iran began, as a combination of factors weighs them down.

The country’s carriers — which swung to a quarterly profit in the beginning of 2026 — are caught in a pincer of higher fuel costs and a price-wary domestic market being eroded by high-speed rail. Jet fuel prices soared after the U.S. and Israel launched attacks on Iran in February.

And while many global peers are hedged against swings in fuel prices, Chinese airlines hedge little of their fuel purchases, making them vulnerable to a harder hit from the prolonged rise in oil prices.

The so-called “Big Three” — Air China, China Eastern and China Southern Airlines — together account for the bulk of domestic capacity and are expected to record a combined net loss of 22 billion yuan ($3.2 billion) in 2026, swinging back into the red after the profitable first quarter, according to HSBC analysts.

Their share priced have fallen around 30% since the war began, among the worst performers in the region, according to LSEG data. Singapore Airlines shares were down 9% as of Thursday over the same period, Korean Air Lines slipped 7%, Japan Airlines down 20%, and ANA Holdings 18%.

Which airlines are being hurt worse by the Iran war — Chinese or Indian carriers?

The surging costs have triggered a wave of international and domestic flight cancellations. Multiple carriers have reduced or suspended international flight services since the outbreak of the war. And during the week ending May 14, domestic passenger flights in China fell 12.7% year-on-year while cancellation rates hit nearly 30%, both sharply worse than seasonal norms, according to Goldman Sachs.

Jet fuel prices increased worldwide after the Iran war started, most of all in Asia-Pacific. Platts, a widely used jet fuel Singapore benchmark, climbed from $93 per barrel in late February to a record $242 per barrel in late March. Prices have since moderated to $163 per barrel, which is still achingly high for the notoriously thin-margined aviation industry.

The Chinese government helps to regulate jet fuel rates, though prices are still linked to international crude oil rates. The country’s ex-factory jet fuel rates surged 74% in April, according to HSBC.

Prices surge, cancellations soar

To cope, many airlines are passing costs along to passengers in the form of higher airfares, fuel surcharges, and higher baggage fees.

Starting April 5, Chinese airlines raised domestic fuel surcharges to 60 yuan for flights under 800 kilometers and 120 yuan for longer routes — up from 10 yuan and 20 yuan previously. A further increase took effect May 16, pushing short-haul surcharges to 90 yuan and long-haul to 170 yuan — a 50% and 42% rise respectively on top of the sixfold April adjustment.

But analysts say this won’t fully absorb the fuel cost shock.

“The fare increases required to fully offset higher fuel expenses are too large to be realistically achieved, particularly in a highly price-sensitive and competitive environment,” said Jason Sum, analyst at DBS Group Research.

Chinese carriers can legally pass through up to 80% of fuel-price increases. Yet, HSBC estimates the Big Three are likely only recouping around 60% of these costs.

“In practice, they often choose not to use the full allowance because doing so could materially weaken demand,” said Parash Jain, HSBC’s global head of transport and logistics research.

The bank estimates that every 10% increase in jet fuel prices would widen the Big Three’s combined losses in 2026 by 38%, “further decoupling the Big 3 from global peers with robust pricing power and hedging strategies.”

Compelling railway alternative

China’s expanding high-speed rail network also undercuts domestic carriers on prices across many key routes, with analysts warning that aggressive fuel surcharges risk demand destruction and China faces that constraint more acutely than most peers.

Passengers wait to board a train at Tengzhou East Railway Station in Tengzhou, east China’s Shandong Province, May 5, 2026.

Li Zhijun | Xinhua News Agency | Getty Images

Southeast Asian markets such as Indonesia and the Philippines have cost-conscious travelers but minimal rail alternatives. While Indonesia has a cap on jet fuel surcharges and deployed temporary subsidies to cushion the shock, airlines there still retain greater pricing power.

Japan and Europe have expansive rail networks, but retain stronger airline pricing power due to stronger consumer spending power and route economics.

India, which has similar demand sensitivity, has seen its airline sector boom partly because high-speed options barely exist.

Indian Railways Minister Ashwini Vaishnaw last week warned at a summit that corridors such as Mumbai-Pune, Hyderabad-Bengaluru, and Bengaluru-Chennai would become “99% dominated by railways.”

Hedging gap

Chinese carriers also lack fuel hedges, leaving them fully exposed to oil price swings.

Why Singapore Airlines is still backing Air India despite an 'awful year': Analyst

China Eastern was the only one of the nation’s Big Three state-owned carriers to manage jet fuel price risk through hedging in 2025. Even that position was thin, according to DBS’s Sum. Air China and China Southern entered the fuel shock with essentially no hedging.

That put Chinese carriers at a disadvantage against better-hedged international peers. Singapore Airlines booked a S$218 million ($170 million) gain from fuel hedging in the second half of its financial year ending March 31.

Hedging doesn’t help with jet fuel shortages, which are hitting Asian carriers the hardest, Willie Walsh, head of the International Air Transport Association, told CNBC in April. Chinese carriers aren’t as affected by the shortage as other Asian airlines, however, owing to vast oil reserves and the country’s status as a jet fuel refiner and exporter.

Who is suffering the most?

As to which Asian airlines are suffering the most, it may be a toss-up between Indian and Chinese carriers.

“In the near term, Indian airlines appear more vulnerable given currency weakness and higher exposure to the Middle East region,” said HSBC’s Jain. “However, over the medium term, we think Chinese carriers are worse off. Indian airlines face less direct substitution from rail and can pass through more of the fuel cost.”

However, Chinese carriers ultimately have the backing of the Chinese government.

“State-owned entities will remain resilient and can continue to raise equity to support their balance sheets, which makes them less vulnerable to bankruptcy than similarly exposed private global carriers,” said Jain.

Choose CNBC as your preferred source on Google and never miss a moment from the most trusted name in business news.

Source

Kelun-Biotech to Present Two Registrational Studies in the Oral Presentation Session on Non-Small Cell Lung Cancer at ASCO 2026

0
  • Sacituzumab tirumotecan (sac-TMT)(佳泰莱®) plus pembrolizumab versus pembrolizumab as first-line treatment for PD-L1 positive advanced NSCLC: Results from the randomized, controlled, registrational Phase III OptiTROP-Lung05 study (Abstract #8506)
  • Efficacy and safety of lunbotinib fumarate (A400/EP0031,宁泰莱®[1]), a next-generation selective RET inhibitor (SRI), from a pivotal registrational Phase Ⅱ study in patients with advanced RET-fusion positive NSCLC (Abstract #8505)

CHENGDU, China, May 22, 2026 /PRNewswire/ — The 2026 American Society of Clinical Oncology (ASCO) Annual Meeting will be held in Chicago from May 29 to June 2, local time. Two registrational studies of the trophoblast cell-surface antigen 2 (TROP2)-directed antibody drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT)(佳泰莱®) and the next‑generation selective rearranged during transfection (RET) inhibitor lunbotinib fumarate (A400/EP0031,宁泰莱®) from Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (“Kelun-Biotech” or the “Company”, 6990.HK) have been selected for oral presentation session on Lung Cancer – Non-Small Cell Metastatic. The full text of the related abstracts were published on the ASCO official website[2] on May 21, 2026, local time. Key highlights are summarized as follows:

Study 1

Sacituzumab tirumotecan (sac-TMT) plus pembrolizumab versus pembrolizumab as first-line treatment for PD-L1 positive advanced non-small cell lung cancer (NSCLC): Results from the randomized, controlled Phase III OptiTROP-Lung05 study, to be presented as an oral presentation scheduled on May 29, 2026, 3:12 PM-3:24 PM CDT (Abstract #8506: Lung Cancer – Non-Small Cell Metastatic)

A total of 413 patients with previously untreated locally advanced or metastatic NSCLC without epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK) alterations and with programmed death ligand 1 (PD-L1) positive (defined as tumor proportion score (TPS) ≥1%), covering both squamous and non‑squamous histologies, were enrolled and randomized (1:1) to receive sac-TMT (4mg/kg Q2W) plus pembrolizumab (400mg Q6W) or pembrolizumab monotherapy (400mg Q6W). The primary endpoint was progression‑free survival (PFS) assessed by blinded independent central review (BICR), and the key secondary endpoint was overall survival (OS). As of September 29, 2025, the median follow-up was 10.5 months.

The results demonstrated that:

  • Significant PFS improvement: PFS assessed by BICR was significantly improved in the sac-TMT plus pembrolizumab group compared with the pembrolizumab group, with a median PFS of not reached (NR) versus 5.7 months (hazard ratio (HR)=0.35; 95% confidence interval (CI): 0.26–0.47; p<0.0001).
  • Substantially higher response rate: The objective response rate (ORR) assessed by BICR was 70.2% in the sac-TMT plus pembrolizumab group versus 42.0% in the pembrolizumab group.
  • Positive OS trend though immature (HR=0.55; 95% CI: 0.36–0.85).
  • Consistent benefit across prespecified subgroups: the HR for PFS in patients with PD-L1 TPS 1-49% and TPS ≥ 50% were 0.28 (95% CI, 0.19-0.41) and 0.47 (95% CI, 0.29-0.77), respectively; the HR for PFS in patients with non-squamous and squamous NSCLC were 0.28 (95% CI, 0.18-0.43) and 0.44 (95% CI, 0.29-0.66).

In terms of safety, grade≥ 3 treatment-emergent adverse events (TEAEs) occurred in 55.3% of patients in the sac-TMT plus pembrolizumab group versus 31.4% in the pembrolizumab group. TEAEs leading to permanent discontinuation of sac-TMT and pembrolizumab occurred in 3.8% and 5.3% of patients, respectively, while TEAEs leading to permanent discontinuation occurred in 4.9% of patients in the pembrolizumab group.

OptiTROP-Lung05 is the first Phase III clinical study demonstrating a significant improvement in PFS and a positive trend in OS with an ADC combined with pembrolizumab compared to pembrolizumab in first-line treatment for PD-L1 positive advanced NSCLC. Based on these results, a supplemental New Drug Application (sNDA) for this combination regimen has been accepted for review and included in the priority review and approval process by the National Medical Products Administration (NMPA) in China.

Study 2

Efficacy and safety of lunbotinib (A400/EP0031), a next-generation selective RET inhibitor (SRI), from a pivotal phase Ⅱ study in patients with advanced RET-fusion positive non-small cell lung cancer (NSCLC), to be presented as an oral presentation scheduled on May 29, 2026, 2:36 PM-2:48 PM CDT (Abstract #8505: Lung Cancer – Non-Small Cell Metastatic)

As of October 29, 2025, 71 patients with prior platinum-based chemotherapy and immunotherapy (pre-treated patients) and 92 patients who had not received prior systemic therapy (treatment-naïve patients) were enrolled, with median follow-up of 22.6 and 20.7 months.

The study demonstrated that:

  • Independent Review Committee (IRC)-assessed confirmed ORR was 87.1% (95% CI: 77.0-93.9) in pre-treated patients and 81.3% (95% CI: 71.8-88.7) in treatment-naïve patients;
  • Median PFS was 27.5 months in pre-treated patients (immature) and NR in treatment-naïve patients, with 24-month PFS rates of 52.1% and 59.9%, respectively;
  • Median OS was not reached in either group, with 24-month OS rates of 65.7% in pre-treated patients and 74.1% in treatment-naïve patients.
  • Among patients with baseline brain metastases (23 pre-treated, 16 treatment-naïve), ORR was 82.6% and 75.0%, respectively, and 6 patients in each cohort had complete intracranial response.

The safety profile was manageable, with no new signals identified. Grade ≥ 3 treatment-related adverse events (TRAEs) occurred in 40.5% of patients. Only two patients (1.2%) permanently discontinued treatment due to TRAEs. No fatal TRAEs occurred.

Based on the results of this study, the new drug application (NDA) for lunbotinib fumarate for the treatment of adult patients with RET fusion-positive locally advanced or metastatic NSCLC has been accepted for review by the NMPA.

About sac-TMT(佳泰莱®)

Sac-TMT, a core product of the Company, is a novel human TROP2 ADC in which the Company has proprietary intellectual property rights, targeting advanced solid tumors such as NSCLC, breast cancer (BC), gastric cancer (GC), gynecological tumors and genitourinary tumors, among others. Sac-TMT is developed with a unique, bifunctional linker that maximizes payload delivery to tumor cells both through its irreversible connection with the anti-TROP2 monoclonal antibody sacituzumab and its pH-sensitive cleavage from a belotecan-derivative topoisomerase I inhibitor payload in the lysosome, with a drug-to-antibody-ratio (DAR) of 7.4. Sac-TMT specifically recognizes TROP2 on the surface of tumor cells by recombinant anti-TROP2 humanized monoclonal antibodies, which is then endocytosed by tumor cells and releases the payload KL610023 intracellularly. KL610023, as a topoisomerase I inhibitor, induces DNA damage to tumor cells, which in turn leads to cell-cycle arrest and apoptosis. In addition, it also releases KL610023 in the tumor microenvironment. Given that KL610023 is membrane permeable, it can enable a bystander effect, or in other words kill adjacent tumor cells.

In May 2022, the Company licensed the exclusive rights to MSD (the tradename of Merck & Co., Inc, Rahway, NJ, USA) to develop, use, manufacture and commercialize sac-TMT in all territories outside of Greater China (which includes Mainland China, Hong Kong, Macao and Taiwan).

To date, four indications for sac-TMT have been approved and marketed in China for: 1) unresectable locally advanced or metastatic triple‑negative breast cancer (TNBC) who have received at least two prior systemic therapies (at least one of them for advanced or metastatic setting); 2) EGFR mutant-positive locally advanced or metastatic non-squamous NSCLC following progression on EGFR–tyrosine kinase inhibitor (EGFR-TKI) therapy and platinum-based chemotherapy; 3) EGFR mutant-positive locally advanced or metastatic non-squamous NSCLC who progressed after treatment with EGFR-TKI therapy; 4) unresectable or metastatic hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) (Immunohistochemistry (IHC) 0, IHC 1+ or IHC 2+/In Situ Hybridization (ISH)-) BC who have received prior endocrine therapy and at least one line of chemotherapy in advanced setting. The first two indications above have been included in China’s National Reimbursement Drug List (NRDL). This inclusion is expected to bring clinically meaningful benefits to a greater number of patients with BC and NSCLC. Additionally, sac-TMT has been granted six Breakthrough Therapy Designations (BTDs) by the NMPA.

Sac-TMT is the world’s first TROP2 ADC drug approved for marketing in lung cancer.  A new indication application for sac-TMT in combination with pembrolizumab (KEYTRUDA®[3]) as first‑line treatment for locally advanced or metastatic NSCLC who have PD-L1 TPS≥1% and are EGFR-negative and ALK-negative has been accepted for review by the NMPA, and has entered the priority review and approval process. As of today, Kelun-Biotech has initiated 9 registrational clinical studies in China. MSD is evaluating 17 ongoing global Phase III clinical studies of sac-TMT as a monotherapy or in combination with pembrolizumab or other anti-cancer agents for several types of cancer. These studies are sponsored and led by MSD.

About Lunbotinib Fumarate (A400/EP0031,宁泰莱®)

Lunbotinib fumarate is a novel, next-generation selective RET inhibitor for NSCLC, medullary thyroid cancer (MTC) and other solid tumors with a high prevalence of RET alterations. The NDA of lunbotinib fumarate has been accepted for review by the NMPA of China for the treatment of adult patients with RET-fusion positive locally advanced or metastatic NSCLC. The Company is also conducting a Phase Ib/II clinical study in China for the treatment of RET-positive solid tumors.

In March 2021, the Company granted Ellipses Pharma Limited, a U.K.-based international oncology drug development company, an exclusive license to develop, manufacture and commercialize this agent outside Greater China and certain Asian countries. In April 2024, lunbotinib fumarate was cleared by the Food and Drug Administration (FDA) to progress into a Phase II clinical trial (NCT05443126) which is currently recruiting in the United States, United Kingdom, Europe and United Arab Emirates, where it is being evaluated as a monotherapy and in combination with chemotherapy in RET fusion positive advanced NSCLC.

About Kelun-Biotech

Kelun-Biotech (6990.HK) is a holding subsidiary of Kelun Pharmaceutical, which focuses on the R&D, manufacturing, commercialization and global collaboration of innovative biological drugs and small molecule drugs. Kelun-Biotech focuses on major disease areas such as solid tumors, autoimmune, and metabolic diseases, and in establishing a globalized drug development and industrialization platform to address the unmet medical needs in China and the rest of world. Kelun-Biotech is committed to becoming a leading global enterprise in the field of innovative drugs. At present, Kelun-Biotech has more than 30 ongoing key innovative drug projects, of which 4 projects have been approved for marketing, 1 project is in the NDA stage and more than 10 projects are in the clinical stage. Kelun-Biotech has established one of the world’s leading proprietary ADC and novel DC platforms, OptiDC™, and has 2 ADC projects approved for marketing, and multiple ADC and novel DC assets in clinical or preclinical research stage. For more information, please visit https://en.kelun-biotech.com/.

Source

Touching Hearts Through Cinema — Chinese Film “My World Without Me” Earns High Praise at Cannes

0

79th Festival de Cannes • Spotlight on Chinese Cinema • China Pavilion

CANNES, France, May 21, 2026 /PRNewswire/ — On May 14 (local time), the Chinese film My World Without Me, directed by Tian Hairong, was screened at the Palais des Festivals in Cannes. Selected for the International Promotional Screening Unit of the 79th Festival de Cannes, the film garnered warm applause and high praise from audiences around the world, as well as invaluable feedback and insights.

The creative team of "My World Without Me" at the China Pavilion panel — "The Power of Images and Care for the Soul" — at the 79th Festival de Cannes.
The creative team of “My World Without Me” at the China Pavilion panel — “The Power of Images and Care for the Soul” — at the 79th Festival de Cannes.

Following the screening, the film’s creative team joined a themed panel at the China Pavilion titled “The Power of Images and Care for the Soul,” engaging in a heartfelt dialogue with filmmakers and audiences from across the globe on the themes of life and adversity — resonating deeply with the tender hearts of people from all cultural backgrounds. The panel was hosted by China Film Foundation & China Film Association and organized by China Film Foundation • Wutianming Film Fund.

About the Film and Its Creative Team

My World Without Me is directed and headlined by Tian Hairong, with Zhang Hanyu serving as executive producer for the first time. The film was crafted over nearly seven years with exceptional care and dedication. It focuses on the contemporary community of people with hidden depression, conveying love and hope through the quiet spaces of daily life and the gentle light found in ordinary moments. Confronting suffering head-on, the film exemplifies the restrained aesthetics and humanistic warmth characteristic of Chinese realist cinema, offering an Eastern perspective on mental health narratives.

Tian Hairong is a graduate of the Performance Department of the Shanghai Theatre Academy and a renowned actress and producer in mainland China. She received the Golden Deer Award for Best Actress at the Changchun International Film Festival for Romantic Girl, the Best Actress award at the Nordic International Film Festival for The Spirit of a Generation: Tang Qunying, and the Best Supporting Actress award at the 12th Macao International Film Festival. Tian expressed her hope that through international platforms such as Cannes, the world will come to feel the warmth and depth of Chinese cinema.

International Recognition

French director Frédéric Oberlin praised the film for using a uniquely Eastern mastery of emotion to deliver silent feelings directly to the heart. Sinologist Luisa Prudentino noted after viewing the film that its sincere emotional core transcends cultural barriers, protecting the dignity of life and becoming a warm thread of empathy connecting different civilizations.

The film is set to continue participating in further international film festivals, using the power of cinema to build bridges of cultural communication and to help Chinese stories reach the world in a manner rich with humanistic care.

Source

Archaeologists uncover massive ancient site during rail project, including rare Roman find

0

NEWYou can now listen to Fox News articles!

Archaeologists in Central Europe have uncovered more than 1,000 ancient artifacts ahead of railway construction, including a rare Roman-era tool used to make metal wire.

The news was announced in an April press release from the Archaeological Center Olomouc (ACO), a research institution in the Czech Republic.

The finds were made along a roughly three-quarter-mile stretch that will serve as part of a high-speed railway between Nezamyslice and Kojetín, two Czech towns in the Haná River valley.

TREASURE TROVE OF PRICELESS CELTIC GOLD AND SILVER COINS UNEARTHED AT ‘SECRET’ EUROPEAN SITE

The discoveries span from the Early Bronze Age to the Roman era. Excavations were carried out between April and October 2025.

Nikola Jandová, a spokesperson for ACO, said in a statement that the site “ranks among exceptionally rich settlement complexes in this part of the Haná region.”

Aerial of site next to Roman drawplate

Archaeologists in the Czech Republic uncovered more than 1,000 artifacts spanning multiple eras during railway construction work. Seen right, a Roman drawplate. (Archaeological Centre Olomouc, Andrea Šindlerová)

Remains from two Bronze Age cultures — the Věteřov and Urnfield cultures — were found, along with evidence of the Iron Age La Tène culture.

The earliest settlement dates to the Věteřov culture, with archaeologists uncovering the remains of wooden homes. The Věteřov and Urnfield cultures lived in the area in roughly 1800-1500 B.C. and 1300-800 B.C., respectively.

ANCIENT ROMAN FORT YIELDS 2,000-YEAR-OLD FRUIT THAT SURVIVED THE CENTURIES, PLUS OTHER TREASURES

“Following destructive fires, fragments of wall plaster survived as reddened fired clay, known as daub,” the statement noted.

“Some fragments show smoothed surfaces with traces of external decoration, while others preserve impressions of wattle on the inner side.”

“These finds … indicate the presence of a specialized bronze-working workshop.”

Archaeologist Pavel Moš said in a statement that the details of the houses were preserved in the daub, with some surface finishing traces still visible.

Excavators also found two Věteřov graves, including one containing an adult and a child, which will undergo analysis.

CLICK HERE TO SIGN UP FOR OUR LIFESTYLE NEWSLETTER

Among the Urnfield culture remains, archaeologists unearthed four graves — as well as one with six human skulls “found placed side by side within the fill of the feature.”

They also found crucible fragments and stone molds used to craft bronze objects, as well as a small assemblage of bronze artifacts, including axes, pins, a bracelet and a knife.

Aerial birds eye view of construction site with various pits

Excavations along a planned high-speed rail route revealed remains from the Bronze Age through the Roman era. (Archaeological Centre Olomouc, Andrea Šindlerová)

“These finds date to the end of the Bronze Age and the Early Iron Age and indicate the presence of a specialized bronze-working workshop,” the statement read.

Archaeologists also uncovered a lime kiln, likely used by Germanic tribes during the Roman era for wall finishing or pottery decoration in the first to fourth centuries A.D.

CLICK HERE FOR MORE LIFESTYLE STORIES

The most unusual artifact was a Roman drawplate used to pull and thin the metal wire, officials said.

The discovery is considered rare in Central Europe.

View of ancient stone molds found at site

Archaeologists uncovered stone molds used to shape bronze objects, pointing to specialized metalworking at the site. (Archaeological Centre Olomouc, Andrea Šindlerová)

Though the drawplate is considered well-preserved, archaeologist Pavel Moš noted that “corrosion residues are present in its perforations, and traces of drawn metal wires may be preserved.”

He added, “The drawplate will be subjected to spectrometric analysis to determine the material of the wire.”

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

The draw wire, he went on, “could have been used, for example, in the production of chain mail.”

All artifacts will undergo lab analysis and preservation, with results expected to be released over time.

View of skeleton in pit burial

Excavators found graves linked to the Věteřov culture, including one burial containing both an adult and a child. (Archaeological Centre Olomouc, Andrea Šindlerová)

Fox News Digital reached out to ACO for additional information.

The latest discovery follows a similar one made by ACO archaeologists in the Czech Republic.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

Last year, officials announced they found multiple military graves during highway construction, with the oldest grave dating to the 1745 Battle of Žďár during the Second Silesian War.

Source

Adelaide Crows cop ribbing for using heater on the bench during Tasmania game

0

AFL commentators have been left in shock after spotting an unusual addition to the Adelaide Crows’ bench during a chilly Thursday night at UTAS Stadium in Tasmania.

Star Seven caller Brian Taylor — a famous hard man back in his day — could not believe what he was seeing when the players on the bench were spotted next to a heater.

“Have a look at that heater on the Crows bench,” 7NEWS chief AFL reporter Mitch Cleary pointed out in the first quarter of the Crows’ clash with Hawthorn.

Know the news with the 7NEWS app: Download today Arrow

“Right now we’re seven and a half degrees. (7NEWS weather expert) Jane Bunn tells me we’re going to get down to 4C as the game progresses, but the Crows are prepared tonight. They’ve brought their own heater.”

BT was in immediate shock.

“Oh, please. Is that for the staff or the players? Surely that’s not for the players,” Taylor said, while Cleary noted that key forward Riley Thilthorpe was “pretty close to it”.

Hawthorn players used an electric blanket on the bench, while the Crows kept warm with a plug-in heater.
Hawthorn players used an electric blanket on the bench, while the Crows kept warm with a plug-in heater. Credit: Seven

Taylor: “Please. I’ve seen it all now. I’m shocked to see a heater on the bench. I’ve got to say, this is absolutely out of control.”

The Crows doctor later confirmed the heater was indeed for staff and to help keep the players warm.

“I’ve heard of buckets of hot water, I’ve heard of hand warmers, a hot water bottle … the electric blanket will be there next,” Taylor said.

Luke Hodge noted that English Premier League clubs have seat warmers for their players, but Taylor was having none of it.

Taylor: “Well, we have those in our car … Unbelievable. What is wrong with a dressing gown? I can see (Hamish McLachlan) as a dressing gown sort of guy.”

Back in Taylor’s playing days players did in fact wear dressing gowns when they were on the bench.

Cleary also revealed that the Crows’s had an interesting start to the game.

“All year the Crows have been worried about their starts to games. A few weeks ago, (coach) Matthew Nicks joked that they were stuck on the bus to start the game.,” Cleary said

“Well, tonight they literally were (stuck on a bus). A separate car crash in town forced the Crows players to walk the last couple of 100 meters to the ground. it might be the omen they needed.”

To be fair to Adelaide, they weren’t the only ones going to extra lengths to stay warm.

Hawthorn players — who were on the bench — were had an electric blanket across their legs.

Source